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食管癌放疗过程中食管移动度分析

Analysis of Esophageal Mobility during Radiotherapy for Esophageal Cancer

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【作者】 张云波李敬郑丽萍李锦秋张建光于会明

【Author】 ZHANG Yun-bo;LI Jing;ZHENG Li-ping;LI Jin-qiu;ZHANG Jian-guang;YU Hui-ming;Zibo Bashan Wanjie Hospital;Department of Radiation & Oncology,Key Laboratory of Carcinogenesis and Translational Research ( Ministry of Education) ,Cancer Hospital & Institute,Peking University;Department of Radiotherapy,The First Affiliated Hospital of Hebei North University;

【通讯作者】 于会明;

【机构】 淄博岜山万杰医院北京大学肿瘤医院与研究所肿瘤发生与转化研究重点实验室(教育部)放射肿瘤科河北北方学院附属第一医院放疗科

【摘要】 目的探讨食管癌在放疗过程中位置的移动度范围。方法选取17例食管癌患者,通过定位CT和CBCT在隆突层面测量,以脊柱正中线与脊柱前缘水平线垂直点为零刻度点,测量食管左右和前后方向的移动度,分别比较差值。结果左右方向最大值为2.61 cm,最小值为-1.51 cm,最大差值为2.53 cm,最小差值为0.3 cm。食管位于最左侧均值为1.40 cm,最右侧均值为0.34 cm。两组比较差值为(1.069±0.577) cm, 95%CI为0.771~1.365 cm,t=7.630,P<0.001。在前后方向最大值为1.93 cm,最小值为-0.63 cm,最大差值为1.22 cm,最小差值为0 cm。食管位于最前侧均值为0.98 cm,最后侧均值为0.57 cm。两组比较差值为(0.414±0.278) cm, 95%CI为0.271~0.557 cm,t=6.153,P<0.001。结论食管在左右及前后方向移动度较大,在放疗靶区勾画及治疗定位需要考虑食管移动度。

【Abstract】 Objective To investigate the range of position movement of esophageal cancer during radiotherapy. Methods 17 patients with esophageal cancer were selected. The protuberance level was measured by location CT and CBCT. The vertical point between the spinal midline and the horizontal line of the anterior edge of the spine is the zero scale point. The left and right and anteroposterior displacement of esophagus were measured and compared. Results The maximum value of the left and right direction is 2.61 cm, the minimum value is-1.51 cm, the maximum difference is 2.53 cm, and the minimum difference is 0.3 cm. The mean value of esophagus located on the left side was 1.40 cm, and that on the right side was 0.34 cm. The difference between the two groups was(1.069±0.577) cm, 95% CI was 0.771~1.365 cm, t= 7.630, P<0.001. In the front and back direction, the maximum value is 1.93 cm, the minimum value is-0.63 cm, the maximum difference is 1.22 cm, the minimum difference is 0. The mean value of the esophagus located in the front was 0.98 cm, and that of the rear side was 0.57 cm. The difference between the two groups was 0.414±0.278 cm, 95% CI was 0.271~0.557 cm, t=6.153,P<0.001. Conclusion The esophageal mobility is large in the left and right and anteroposterior directions, and should be considered in the target delineation and treatment positioning of radiotherapy.

【关键词】 食管癌放疗移动度
【Key words】 esophageal cancerradiotherapymobility
【基金】 国家自然科学基金(81672969);国家重点研发计划项目(2018YFE0114100)
  • 【文献出处】 食管疾病 ,Journal of Esophageal Diseases , 编辑部邮箱 ,2021年02期
  • 【分类号】R735.1
  • 【下载频次】39
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