【摘要】 目的:探讨胆道闭锁产前超声表现及临床预后分析。方法:回顾性分析了18例经确诊的胆道闭锁病例其产前超声及出生后临床随访观察资料。结果:8/18(44.4%)的病例产前发现了超声软指标阳性,5/18(27.8%)的病例发现了器官结构异常,5/18(27.8%)的病例产前超声无阳性发现。出生后均行手术明确了胆道闭锁的诊断及分型。随访发现8/18(44.4%)患儿于婴幼儿期或儿童期行肝移植治疗,10/18(55.6%)患儿自体肝生存至今。结论:产前超声可表现为软指标阳性或器官结构异常,对于胆道闭锁的诊断具有重要提示作用。胆道闭锁患儿出生后均需及时手术治疗,最终部分需要在儿童期行肝移植,以延长其生存期。更多还原

【Abstract】 Objective: To explore the prenatal ultrasonography characteristics and postal prognosis of biliary atresia.Methods: The data of prenatal and postnatal follow-up ultrasound were analyzed in 18 cases of biliary atresia retrospectively.Results: There were 8/18(44.4%) cases with ultrasound soft index and 5/18(27.8%) cases with organizational structure abnormalities. 5/18(27.8%) cases had no obvious manifestations in prenatal ultrasound. The final diagnosis and classification of biliary atresia were confirmed after operations. Up to now, 8/18(44.4%) cases were treated with liver transplantation in infancy or childhood, and 10/18(55.6%) cases had survived with their autologous livers. Conclusion: Some biliary atresia cases showed ultrasound soft index or organ structure abnormality, which were helpful for the diagnosis of gallbladder atresia. Children with gallbladder atresia should be operated in time after birth. Liver transplantation were needed finally for some children for better survival.更多还原