【摘要】 玫瑰痤疮是一种好发于面中部的慢性炎症性皮肤病,以面部阵发性潮红、持久性红斑、丘疹脓疱等为主要表现,其病因及发病机制尚不清楚。关于微生物在玫瑰痤疮中的致病作用存在争议。微生物一般通过破坏皮肤屏障、诱发炎症反应、分泌生物活性因子及毒素等方式介导玫瑰痤疮的发生。本文总结国内外近年关于微生物与玫瑰痤疮发病的相关研究,进一步揭示微生物与玫瑰痤疮存在密切关系,为临床治疗提供参考。更多还原

【Abstract】 Rosacea is a chronic inflammatory skin disease that often occurs in the middle of the face. It is characterized by facial paroxysmal flushing, persistent erythema, papules and pustules. Its etiology and pathogenesis are still unclear. There is much controversy about the role of microorganisms in the pathogenesis of rosacea. Microorganisms generally mediate the occurrence of rosacea by destroying skin barrier, inducing inflammation, secreting bioactive factors and toxins. This paper summarizes the related studies about microorganisms in the pathogenesis of rosacea in recent years in order to provide a reference for clinical treatment.更多还原