【摘要】 目的探讨一般人群中有早发高血压家族史人群与高血压之间的关系。方法采用分层多阶段随机抽样的方法,对陕西省15岁及以上人群进行有效问卷调查及体格检查,运用logistic回归模型分析早发高血压家族史对高血压的影响。结果有早发高血压家族史的者的高血压患病率是31.9%,无早发高血压家族史者的高血压患病率是27.3%,两者比较差异有统计学意义(P<0.001)。在有早发高血压家族史人群的收缩压和舒张压水平都高于没有早发家族史的人群,差异有统计学意义(P<0.001);Logistic回归分析显示,在全人群中患高血压的风险,具有早发高血压家族史是没有早发高血压家族史人群的1.394倍(95%CI:1.108-1.754),差异有统计学意义(P<0.05)。在不同性别、年龄组和地区的亚组分析结果,我们发现在女性、年龄≥60岁和城市地区患高血压的风险,有早发高血压家族史者分别是没有早发高血压家族史者的1.871倍、3.166倍和1.413倍,差异有统计学意义(P<0.05)。结论早发高血压家族史是高血压的危险因素,有早发高血压家族史人群的高血压患病率显著高于没有早发高血压家族史的人群。加强高血压健康教育,对有早发高血压家族史人群预防高血压有重要意义。更多还原

【Abstract】 Objective To explore the relationship between family history of early onset hypertension and hypertension in general population.Methods Stratified multi-stage random sampling method was used to conduct effective questionnaire survey and physical examination on the population aged 15 and above in Shaanxi Province.Logistic regression model was used to analyze the influence of family history of early onset hypertension on hypertension.Results The prevalence of hypertension was 31.9% in patients with family history of early-onset hypertension and 27.3% in patients without family history of early-onset hypertension.There was significant difference between the two groups(P<0.001).The systolic blood pressure and diastolic blood pressure levels of people with family history of early-onset hypertension were higher than those without family history of early-onset hypertension, and the difference was statistically significant(P<0.001);logistic regression analysis showed that the risk of hypertension in the whole population with family history of early-onset hypertension was 1.394 times that of people without family history of early-onset hypertension(95%CI:1.108-1.754,P<0.05).In the subgroup analysis results of different gender, age groups and regions, we found that the risk of hypertension in women, age ≥ 60 years old and urban areas was 1.871 times, 3.166 times and 1.413 times of those without family history of early-onset hypertension, respectively, and the difference was statistically significant(P<0.05).Conclusion Family history of early-onset hypertension is a risk factor for hypertension.The prevalence of hypertension in people with family history of early-onset hypertension is significantly higher than that in people without family history of early-onset hypertension.Strengthening the health education of hypertension is of great significance for the prevention of hypertension among people with family history of early-onset hypertension.更多还原