【摘要】 肌少症是一种增龄性的老年综合征,以全身性肌肉力量、质量下降和机体功能减退为主要表现,与临床不良结局相关。肌少症发病机制复杂,包括与衰老相关的合成代谢激素、运动神经元缺失、肌卫星细胞凋亡、炎症通路、线粒体功能障碍等。炎症是肌少症的一个重要病理生理过程,笔者就肌少症与炎症的关系进行简要综述。更多还原

【Abstract】 Sarcopenia, the age-dependent decline of muscle mass and performance, is a common condition among elderly population and is related to numerous adverse health outcomes.Causes of sarcopenia are generally attributable to the natural processes of aging, which are not entirely understood and are multifaceted.Inflammation is considered as a major pathological causes of human sarcopenia.This review describes the effect of inflammation in skeletal muscle tissue function and possible mechanisms sarcopenia.更多还原