【摘要】 胰胆管合流异常(pancreaticobiliary maljunction, PBM)与胆道恶性肿瘤的相关性已有大量文献报道。胰胆管返流也可发生在胰胆管合流正常的病人,即隐匿性胰胆管返流(occult pancreaticobiliary reflux, OPR)。OPR早期无特殊的临床表现,常规的影像学检查不能诊断OPR,但多项研究表明,OPR可引起多种胆道系统疾病,特别是与胆囊癌的发生密切相关。本文对OPR的研究进展进行综述。更多还原

【Abstract】 Recently, plenty of literature reported that pancreaticobiliary maljunction(PBM) was associated with biliary malignancies.With the deepening of the research, it has been found that pancreaticobiliary reflux also occurs in patients with normal pancreaticobiliary junction(occult pancreaticobiliary reflux, OPR).There are few reports on the correlation between OPR and biliary diseases up to now.The incidence of OPR is still not clear, and the clinical manifestation of OPR in the early stage is not characteristic.OPR cannot be diagnosed by routine imaging examination.However, some studies have shown that OPR was associated with a variety of biliary diseases and play a role in the development of gallbladder cancer.So related disciplines should attach importance to OPR.In this paper, we review the progress in the research of OPR.更多还原