【摘要】 目的研究血清D-二聚体(D-D)联合血管内皮生长因子(VEGF)检测对多发肋骨骨折术后深静脉血栓(DVT)预测价值。方法多发肋骨骨折病人92例,根据术后是否发生DVT将其分为发生组、未发生组。比较两组临床资料;Logistic回归分析法分析DVT影响因素;绘制受试者工作曲线(ROC),分析血清D-D联合VEGF对DVT预测价值。结果发生组年龄≥60岁、糖尿病史、高血压史、静脉曲张史构成比,血清D-D、VEGF高于未发生组,手术时间长于未发生组,差异有统计学意义(P<0.05);经Logistic回归分析,年龄≥60岁、糖尿病、手术时间、血清D-D、VEGF均是DVT发生影响因素(P<0.05);ROC结果显示,血清D-D、VEGF单独及联合预测DVT的AUC分别为0.741、0.705、0.796。结论血清D-D联合VEGF预测多发肋骨骨折术后DVT的效能较高。更多还原

【Abstract】 Objective To study the value of serum D-D combined with VEGF in predicting the risk of DVT after multiple rib fractures.Methods Ninety two patients with multiple rib fractures in our hospital were selectedand divided into the occurrence group and the non-occurrence group according to whether DVT occurred.The differences in clinical data were compared.Logistic regression analysis method to analyze the influencing factors of DVT.ROC to analyze the value on the risk of DVT.Results The ratio of age≥60 years old, history of diabetes, history of hypertension, and history of varicose veins, serum D-D and VEGF of the occurrence group were higher than those of the non-occurring group, of which the operation time was longer than that of the non-occurring group(P<0.05).Logistic regression analysis showed that age≥60 years old, diabetes, operation time, serum D-D,VEGF were all influencing factors of DVT(P<0.05).ROC results showed that the AUC of serum D-D and VEGF alone and combined to predict DVT were 0.741,0.705,0.796,respectively.Conclusion Serum D-D combined with VEGF are highly effective in predicting the occurrence of DVT after multiple rib fractures.更多还原