【摘要】 目的:探讨铒激光在口腔软硬组织中的临床效果及对消融率和应激反应的影响。方法:选择2018年3月～2020年1月口腔软硬组织患者94例作为研究对象,随机数字表法分为两组,各47例。对照组采用手术切除治疗,观察组采用铒激光治疗;于术后14 d评估治疗效果并完成6个月随访,比较两组围术期指标、视觉模拟评分量表(VAS)评分、伤口愈合、手术时间、应激反应、消融率及安全性。结果:两组治疗前VAS评分、伤口愈合时间差异无统计学意义(P>0.05);观察组治疗时间、持续疼痛时间、治疗出血量及治疗后1 d、3 d VAS评分均短(低)于对照组(P<0.05);观察组治疗后14 d NO、Cor水平低于对照组,SOD水平高于对照组(P<0.05)。观察组治疗后1、3、6个月消融率均高于对照组(P<0.05)。观察组与对照组治疗过程中感染、创缘红肿及咽部疼痛发生率差异均无统计学意义。结论:铒激光用于口腔软硬组织中能创伤较小,能减轻疼痛,缩短手术及疼痛持续时间,降低应激发生,提高软硬组织消融率,且安全性较高。更多还原

【Abstract】 Objective:To investigate the clinical effect of Erbium laser in oral soft and hard tissues and its effect on ablation rate and stress response.Methods:A total of 94 patients with oral soft and hard tissue from March 2018 to January 2020 were selected and randomly divided into two groups with 47 patients in each group.The control group was treated with surgical resection and the observation group treated with Erbium laser.The efficacy of the patients was evaluated 14 days after surgery and the patients were followed up for 6 months.Perioperative indexes, visual analog scale(VAS) score, wound healing, operative time, stress response, ablation rate and safety were compared between the two groups.Results:There was no statistical significance in VAS score and wound healing time between the two groups before treatment(P>0.05).The duration of treatment, duration of pain, treated blood loss, VAS score 1 day and 3 days after treatment in the observation group were all shorter(lower)than those in the control group(P<0.05).And 14 days after treatment, the levels of NO and Cor in observation group were lower than those in control group, SOD level was higher(P<0.05).The ablation rates of observation group at 1,3 and 6 months after treatment were higher than those of control group(P<0.05).There was no statistical significance in the incidence of infection, trauma margin redness and pharyngeal pain between the observation group and the control group.Conclusion:Erbium laser can reduce the pain of patients, shorten the duration of surgery and pain, reduce the occurrence of stress and improve the ablation rate of soft and hard tissue.更多还原