【摘要】 目的研究慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者高分辨率计算机断层扫描(high resolution computedtomography,HRCT)检查肺动脉直径测量值与超声心动图检查肺动脉压数值的相关性,找到一种新的方法评估肺动脉压,为临床评估病情增加新的方法。方法将昆明市第一人民医院2018年5月至2020年5月就诊的77例慢阻肺患者设为试验组,另选同期在昆明市第一人民医院进行健康体检的50例健康者设为对照组,均行胸部HRCT检查测量右侧肺动脉直径、左侧肺动脉直径、肺动脉主干直径,同时行心脏彩超检查,测量右室内径、肺动脉压、主肺动脉内径,将收集数据进行相关性分析。结果 COPD组HRCT检查左、右肺动脉直径、肺动脉主干直径数据均大于正常人组(P <0.05),且COPD各组之间右肺动脉直径、肺动脉主干直径数据存在差异(P <0.05),而左侧肺动脉直径不存在差异(P> 0.05);COPD各组之间超声心动图检查测定右室内径、肺动脉压数值存在差异(P <0.05),而主肺动脉内径不存在差异(P> 0.05);经Pearson直线相关性分析右室内径、肺动脉压、主肺动脉内径测定值与左、右肺动脉直径、肺动脉主干直径数据有明显相关性(P <0.05),且均为正相关。结论 COPD患者肺动脉压数值与肺动脉直径数值有明显相关性,HRCT测量肺动脉主干直径、右肺动脉直径可作为评估肺动脉压的一种方法。更多还原

【Abstract】 Objective The correlation between pulmonary artery diameter measured by high resolution computedtomography(HRCT) and pulmonary artery pressure measured by echocardiography in patients with chronic obstructive pulmonary disease(COPD) was investigated to find a new method to assess pulmonary artery pressure and to add a new method to the clinical assessment of the disease. Methods Seventy-seven patients with stable chronic obstructive pulmonary disease who were seen in Kunming First People’s Hospital from May 2018 to May2020 were set as the test group,and 50 healthy individuals who underwent health checkups in same period were selected as the control group,all of whom underwent chest HRCT to measure right pulmonary artery diameter,left pulmonary artery diameter,and main pulmonary artery diameter,and also underwent cardiac ultrasound to measure right ventricular diameter, pulmonary artery pressure, and main pulmonary artery diameter. The data collected were analyzed for correlation. Results The data of left and right pulmonary artery diameter and main pulmonary artery diameter measured by HRCT in the COPD group were larger than those in the normal group(P < 0.05),and there were differences in the data of right pulmonary artery diameter and main pulmonary artery diameter between the COPD groups(P < 0.05),but not in the left pulmonary artery diameter(P > 0.05);the right intraventricular diameter and pulmonary artery pressure measured by echocardiography were different between the COPD groups(P < 0.05). The right intraventricular diameter,pulmonary artery pressure,and main pulmonary artery diameter were significantly correlated with the left and right pulmonary artery diameters and main pulmonary artery diameter by Pearson linear correlation analysis(P < 0.05), and all were positively correlated. Conclusio There is a significant correlation between the values of pulmonary artery pressure and the values of pulmonary artery diameter in patients with COPD. HRCT measurement of pulmonary artery trunk diameter and right pulmonary artery diameter can be used as a method to assess pulmonary artery pressure.更多还原