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内源性二氧化硫是心血管系统新的具有治疗前景的气体信号分子(英文)

Endogenous sulfur dioxide is a new gasotransmitter with promising therapeutic potential in cardiovascular system

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【作者】 黄娅茜; 张恒; 吕博洋; 唐朝枢; 杜军保; 金红芳;

【Author】 Yaqian Huang;Heng Zhang;Boyang Lv;Chaoshu Tang;Junbao Du;Hongfang Jin;Department of Pediatrics, Peking University First Hospital;Department of Endocrinology, Beijing Chaoyang Hospital, Capital Medical University;Department of Physiology and Pathophysiology, Peking University Health Science Center;Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education;

【通讯作者】 杜军保;金红芳;

【机构】 Department of Pediatrics, Peking University First Hospital; Department of Endocrinology, Beijing Chaoyang Hospital, Capital Medical University; Department of Physiology and Pathophysiology, Peking University Health Science Center; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education;

【摘要】 <正>Sulfur dioxide(SO2) was previously considered only as air pollutant. In 2008, our group first detected the endogenous SO2 generating enzymes as well as its generating pathway in cardiovascular system [1]. Our recent studies have shown that endogenous SO2 plays important cardiovascular physiologic regulatory roles and has pathophysiological significance. As such, we suggested that it serves as a new gasotransmitter [1–4].

【基金】 supported by the National Natural Science Foundation of China (81770422, 81921001, 81970424, 81770278, and82070445);the Beijing Natural Science Foundation (7182168,7191012, and 7171010);Changjiang Scholar Program of Ministry of Education of China (Q2017004)
  • 【文献出处】 Science Bulletin ,科学通报(英文版) , 编辑部邮箱 ,2021年16期
  • 【分类号】R914
  • 【下载频次】157
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