【摘要】 目的:探讨单孔胸腔镜肺叶切除术对早期肺癌患者淋巴结清扫数目及并发症的影响。方法:选取2018年2月～2020年2月收治的早期肺癌患者共80例,按治疗方法将其分为单孔组(37例)和三孔组(43例),单孔组患者采取单孔胸腔镜肺叶切除术进行治疗,三孔组患者采用三孔胸腔镜肺叶切除术进行治疗。比较两组患者各项手术指标、疼痛视觉模拟评分(VAS);对比两组患者术前与术后(术后第1天)的炎性反应指标、术后并发症发生率。结果:单孔组患者术中出血量少于三孔组,切口长度小于三孔组,差异有统计学意义(P<0.05),两组患者手术时间、淋巴结清扫数经比较差异无统计学意义(P>0.05);与术前相比两组患者血清C-反应蛋白(CRP)、降钙素原(PCT)、白细胞介素6(IL-6)水平高于术前,差异有统计学意义(P<0.05),但单孔组低于三孔组,差异有统计学意义(P<0.05);单孔组患者术后并发症总发生率(5.41%)低于三孔组(20.93%),差异有统计学意义(P<0.05)。结论:单孔胸腔镜肺叶切除术与三孔胸腔镜肺叶切除术相比,淋巴结清扫数量相当,更有利于降低手术出血量、缩短切口长度、减轻患者的疼痛,炎性反应小,安全性较高。更多还原

【Abstract】 Objective To investigate the effect of single port thoracoscopic lobectomy on the number of lymph node dissection and complications in patients with early lung cancer.Method A total of 80 patients with early lung cancer admitted to the hospital from February 2018 to February 2020 were selected and divided into single hole group(37 cases)and three hole group(43 cases)according to the treatment method.The patients in the single hole group were treated with single hole thoracoscopic lobectomy, and the three hole group were treated with three hole thoracoscopic lobectomy.The operation indexes, visual analogue scale(VAS)of pain were compared between the two groups; the inflammatory indexes and the incidence of postoperative complications were compared between the two groups before and after operation(the first day after operation).Results The intraoperative blood loss and incision length of the single port group were less than those of the three hole group(P< 0.05).There was no significant difference in the operation time and the number of lymph node dissection between the two groups(P>0.05);the serum levels of C-reactive protein(CRP),procalcitonin(PCT)and interleukin-6(IL-6)in the two groups were higher than those before operation(P< 0.05),but lower in the single port group in the three hole group(P< 0.05),the total incidence of postoperative complications in the single hole group(5.41%)was lower than that in the three hole group(20.93%)(P< 0.05).Conclusion Compared with three port thoracoscopic lobectomy, single port thoracoscopic lobectomy has the same number of lymph node dissection, which is more conducive to reduce the amount of bleeding, shorten the length of incision, reduce the pain of patients, with less inflammatory reaction and higher safety.更多还原