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血常规检验在小细胞性贫血鉴别诊断中的临床价值研究

The Clinical Value of Routine Blood Test in the Differential Diagnosis of Small Cell Anemia

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【作者】 李如森; 耿奇; 董明治;

【Author】 LI Rusen;GENG Qi;DONG Mingzhi;Inspection Center of the First People’s Hospital of Qujing City;

【机构】 云南省曲靖市第一人民医院检验中心;

【摘要】 目的探讨血常规检验在小细胞性贫血鉴别诊断中的临床价值。方法便利选取2018年2月—2020年3月该院收治的小细胞贫血患者120例,采用迈瑞BC-5380全自动血液细胞分析仪血液检验的方法对研究对象的外周血进行检验,依照小细胞性贫血类型将其分为地中海贫血组(研究1组)与缺铁性贫血组(研究2组),各60例,同时选取同时期60名健康人员作为对照组,分别对三组研究对象进行红细胞分布宽度(RDW)、红细胞平均体积(MCV)、血红蛋白(Hb)、红细胞(RBC)、平均红细胞血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC))等血常规指标进行检查,对研究对象的上述指标值进行观察,并比较两组(研究1组与研究2组)血常规患者检测的符合率。结果研究1组患者的Hb(102.34±12.08)g/L、RBC(5.11±0.42)×10~9/L、MCHC(326±6.7)g/L明显高于研究2组(86.19±7.82)g/L、(3.18±0.36)×10~9/L、(274±6.8)g/L,差异有统计学意义(t=8.693、27.025、42.194,P<0.001);研究2组的RDW (17.06±3.08)%明显低于研究1组(23.04±1.04)%,差异有统计学意义(P<0.05);高于对照组(14.19±1.34)%,差异有统计学意义(P<0.05);对照组的Hb(124.56±12.21)%、MCH(30.2±3.87)pg、MCV(90.86±9.34)f L水平明显高于研究1组,差异有统计学意义(P<0.05);高于研究2组患者,差异有统计学意义(P<0.001);研究1组与研究2组患者检测的符合率分别为83.33%(50/60)与66.67%(40/60),白细胞检测结果显示正常率分别为3.33%(2/60)与15%(9/60),差异有统计学意义(χ~2=4.444、4.904,P<0.01)。结论血常规检验在贫血鉴别诊断中的应用具有较高的临床价值,可作为诊断贫血和鉴别贫血类型患者一项检查。

【Abstract】 Objective To explore the clinical value of routine blood tests in the differential diagnosis of small cell anemia.Methods Convenient select 120 patients with microcell anemia admitted to the hospital from February 2018 to March 2020,and use the Mindray BC-5380 automatic hematology analyzer blood test method to test the peripheral blood of the study subjects, according to microcell anemia Types were divided into thalassemia group(study 1 group) and iron deficiency anemia group(study 2 group), each with 60 cases. At the same time, 60 healthy people in the same period were selected as the control group, and red blood cell distribution was performed on the three groups of subjects. Width(RDW), average red blood cell volume(MCV), hemoglobin(Hb), red blood cell(RBC), average red blood cell hemoglobin content(MCH),average red blood cell hemoglobin concentration(MCHC) and other blood routine indicators are checked, and the abovementioned The index values were observed, and the coincidence rates of routine blood tests between the two groups(study 1 and study 2) were compared.Results The Hb(102.34±12.08)g/L, RBC(5.11±0.42)×10~9/L and MCHC(326±6.7)g/L of the study group 1 patients were significantly higher than those of the study group 2(86.19 ±7.82)g/L,(3.18±0.36)×10~9/L,(274±6.8)g/L, the difference was statistically significance(t=8.693, 27.025, 42.194, P<0.001); the RDW(17.06±3.08)% of study 2 group was significantly lower than that of study 1(23.04±1.04)%, and the difference was statistically significant(P<0.05);higher than the control group(14.19 ±1.34)%, the difference was statistically significant(P <0.05); the control group Hb(124.56±12.21)g/L, MCH(30.2±3.87)pg, MCV(90.86±9.34)fl was significantly higher than the study 1 group, the difference was statistically significant(P<0.05); higher than the study 2 group patients, the difference was statistically significant(P<0.001); the coincidence rate of the detection of patients in study 1 and study 2 was 83.33%(50/60) and 66.67%(40/60), the white blood cell test results showed that the normal rate was 3.33%(2/60) and 15%(9/60), and the difference was statistically significant(χ~2=4.444, 4.904, P <0.01).Conclusion The application of routine blood test in the differential diagnosis of anemia has high clinical value, and it can be used as an examination for diagnosing anemia and identifying patients with anemia.

  • 【文献出处】 中外医疗 ,China & Foreign Medical Treatment , 编辑部邮箱 ,2021年20期
  • 【分类号】R446.11;R556
  • 【下载频次】90
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