【摘要】 目的探讨两种不同容量单腔球囊在足月妊娠引产中临床效果比较。方法方便选择2018年1月—2019年12月该院收治的已足月、有引产指征、宫颈评分<6分、无放置宫颈球囊禁忌证的初产妇216名,根据不同球囊注水容量随机分为两组,A组108名采用Foley导尿管球囊促宫颈成熟,注水量为80 mL;B组108名采用一次性球囊宫颈扩张器(爱婴球囊)促宫颈成熟,注水量为150 mL。比较两组孕妇引产前后宫颈Bishop变化、引产时间及分娩结局。结果B组宫颈评分改善优于A组、引产至分娩时间短于A组,差异有统计学意义(t=3.439、3.017,P<0.05);B组自然临产率12.0%高于A组的4.6%,24 h内阴道分娩率96.4%高于A组的87.3%,引产失败率1.9%低于A组的8.3%,差异有统计学意义(χ~2=3.879、4.580、4.694,P<0.05)。但两组在总产程、剖宫产率及母婴不良结局(绒毛膜羊膜炎、产后出血、新生儿早发型败血症、新生儿窒息、新生儿胎粪吸入综合征)等方面比较均差异无统计学意义(P>0.05)。结论两种不同容量单腔球囊在足月妊娠引产中均安全有效,注水量150 mL者在改善宫颈成熟、提高自然临产率及24 h阴道分娩率、缩短引产时间等方面效果更好,可提高引产成功率,同时不会增加母婴不良结局。更多还原

【Abstract】 Objective To investigate the clinical effect comparison of two single-lumen balloons with different capacities in induction of labor in term pregnancy. Methods Conveniently selected a total of 216 primiparas who had been admitted to the hospital from January 2018 to December 2019, who were full-term, had indications for induction of labor, had a cervical score of <6, and had no contraindications for cervical balloon placement, were randomly selected according to different balloon injection volumes, and divided into two groups, 108 primiparas in group A used Foley catheter balloon to promote cervical ripening, with a water injection volume of 80 mL; 108 primiparas in group B used a disposable balloon cervical dilator(baby-friendly balloon) to promote cervical ripening, with a water injection volume of 150 mL. The changes of cervical Bishop, the time of labor induction and the outcome of delivery were compared between the two groups of pregnant women before and after induction of labor. Results The improvement of cervical score in group B was better than that in group A, and the time from labor induction to delivery was shorter than that in group A. The difference was statistically significant(t=3.439, 3.017, P<0.05); the natural labor rate of group B was 12.0% higher than that of group A, 4.6%, the rate of vaginal delivery within 24 h was 96.4% higher than that of group A’s 87.3%, and the failure rate of labor induction was1.9% lower than that of group A’s 8.3%. The difference was statistically significant(χ~2=3.879, 4.580, 4.694, P <0.05).However, there was no statistical difference between the two groups in terms of total labor, cesarean section rate, and adverse maternal and child outcomes(chorioamnionitis, postpartum hemorrhage, neonatal early-onset sepsis, neonatal asphyxia, neonatal meconium aspiration syndrome)(P>0.05). Conclusion Two kinds of single-lumen balloons with different capacities are safe and effective in the induction of labor in full-term pregnancy. The 150 mL water injection is more effective in improving cervical maturity, increasing the natural labor rate and the 24 h vaginal delivery rate, and shortening the labor induction time. The success rate of labor induction will not increase the adverse outcome of the mother and child.更多还原