【摘要】 目的探究新冠肺炎流行期间儿童癌症患者的童年不良经历对消化道症状的影响,分析焦虑情绪、应激的中介作用。方法运用问卷调查法对165例儿童癌症患者进行调查。运用相关分析和结构方程模型探讨童年不良经历、焦虑情绪、应激和消化道症状的关系,检验焦虑情绪、应激在童年不良经历对消化道症状的影响中的中介作用。结果童年不良经历与焦虑情绪、应激和消化道症状呈正相关(r=0.623、0.528、0.455,P<0.01),焦虑情绪、应激和消化道症状呈正相关(r=0.515、0.631,P<0.01)。焦虑情绪、应激在童年不良经历对消化道症状的影响中起完全中介作用。结论新冠肺炎流行期间,童年不良经历通过儿童癌症患者的焦虑情绪、应激影响其消化道症状。更多还原

【Abstract】 Objective To explore the effect of adverse childhood experience( ACE) during the COVID-19 on gastrointestinal symptoms in pediatric patients with cancer,and to analyze the mediating effects of anxiety and stress. Methods A questionnaire was used to investigate 165 cases of pediatric patients with cancer. Correlation analysis and structural equation modeling were used to explore the relationship between ACE,anxiety,stress,and gastrointestinal symptoms,and to test the mediating role of anxiety and stress in the influence of ACE on gastrointestinal symptoms. Results ACE was positively related to anxiety,stress,and gastrointestinal symptoms( r = 0. 623,0. 528,0. 455; P < 0. 01). Anxiety and stress were positively correlated with gastrointestinal symptoms( r = 0. 515,0. 631; P < 0. 01). Anxiety and stress played a fully mediating role in the ACE on gastrointestinal symptoms. Conclusions ACE during the COVID-19 affects the gastrointestinal symptoms of pediatric patients with cancer through anxiety and stress.更多还原