【摘要】 目的探讨腭裂术后腭咽闭合不全(VPI)患者行咽后壁瓣修复术(PFS)后阻塞性睡眠呼吸暂停(OSA)的发生率及严重程度,并探讨手术年龄对OSA发生率及严重程度的影响。方法对82例接受PFS手术的腭裂患者进行回顾性研究,根据患者手术时的年龄分为两组,通过夜间多导睡眠监测(PSG)评估术后至少1.2年(平均6.0年) OSA的发生率及严重程度。结果成人组和儿童组术后OSA的发生率分别为20%和31%,两组间差异无统计学意义(P=0.289)。根据呼吸暂停低通气指数(AHI),将成人组及儿童组测得的OSA患者分为不同的严重程度(轻度、中度、重度),两组间OSA严重程度的差异无统计学意义(P=0.079)。结论本研究表明,腭裂患者行PFS平均术后6.0年,一部分患者依然患有OSA。基于本研究的数据表明,手术年龄对于术后远期OSA的发生率及严重程度无影响。更多还原

【Abstract】 Objective This study aims to investigate the incidence and severity of obstructive sleep apnea(OSA) in cleft patients with velopharyngeal insufficiency(VPI) after pharyngeal flap surgery(PFS) and explore the influence of operation age.Methods A retrospective study was conducted in 82 cleft patients after PFS.The patients were divided into two groups according to their age at the time of surgery.The incidence and severity of OSA were assessed at least 1.2 years(mean 6.0 years) postoperatively by polysomnography(PSG).Results The incidence rates of OSA were 20%in the adult group and 31% in the child group.No significant difference was found between the two groups(P=0.289).Patients with OSA in the adult and child groups were classified into different levels of severity(mild,moderate,severe)according to the apnea hypoventilation index(AHI).No statistically significant difference in the severity of OSA was found between the two groups(P=0.079).Conclusion Some patients still have OSA average of 6.0 years after PFS,and operation ageis unrelated to the incidence and severity of OSA.更多还原