【摘要】 回顾了有机立体化学发展的历史,其间Eliel敎授主写的几本优良的立体化学教科书是适合时势和杰出的著作,特别是1962年出版的"碳化合物立体化学"影响众多的有机化学工作者。对Eliel教授发展的应用杂环手性辅助剂是不对称合成方法之一,对手性辅助剂N-苄基-4,4,7α-三甲基-trans-八氢-1,3-苯并氧氮杂环己烷中间体的制备和其应用,作了较详细的阐述。Eliel敎授杰出的科学成就和他在推广科学全球化贡献作了介绍。更多还原

【Abstract】 Long history of organic stereochemistry was briefly reminisced. A few textbooks of organic stereochemistry written mainly by Prof. Eliel, particularly “Stereochemistry of Carbon Compounds” published in 1962, were very timely and excellent works. Using heterocyclic chiral adjuvant, a method of asymmetric synthesis, was developed by Eliel. Preparation and applications of the chiral adjuvant, N-benzyl-4,4,7α-trimethyl-trans-octahydro-1,3-benzoxazine intermediates, were discussed in detail. Eliel’s scientific contributions to stereochemistry and promoted global connectivity were simply presented.更多还原