【摘要】 目的观察松肌正骨术治疗颈性眩晕(CV)的临床疗效及对脑动脉血流速度的影响。方法将74例CV患者按照随机数字表法分为2组,对照组37例予注射用长春西汀治疗,治疗组37例在对照组治疗基础上应用松肌正骨术治疗,2组均治疗20 d。比较2组疗效;观察2组治疗前后症状评分、疼痛视觉模拟评分(VAS)变化;观察2组治疗前后大脑中动脉(MCA)、大脑前动脉(ACA)、大脑后动脉(PCA)及椎动脉(VA)平均血流速度变化;观察2组治疗前后血浆神经肽Y(NPY)、内皮素-1(ET-1)、降钙素基因相关肽(CGRP)水平变化。结果治疗组总有效率91.89%(34/37),对照组总有效率67.57%(25/37),治疗组疗效优于对照组(P<0.05)。2组治疗后眩晕、头痛、恶心呕吐、颈部僵硬症状评分均较本组治疗前降低(P<0.05),且治疗组降低更明显(P<0.05)。2组治疗后疼痛VAS均较本组治疗前降低(P<0.05),且治疗组降低更明显(P<0.05)。2组治疗后MCA、ACA、PCA及VA平均血流速度均较本组治疗前升高(P<0.05),且治疗组升高更明显(P<0.05)。2组治疗后NPY、ET-1水平均较本组治疗前降低(P<0.05),CGRP水平较本组治疗前升高(P<0.05);治疗后治疗组NPY、ET-1水平均低于对照组(P<0.05),CGRP高于对照组(P<0.05)。结论松肌正骨术治疗CV能提高脑动脉血流速度,改善患者眩晕、头痛、恶心呕吐、颈部僵硬症状,提高疗效。更多还原

【Abstract】 Objective To observe the curative effect of muscle relaxation and bone-setting techniques for cervical vertigo(CV)and how it impacts on cerebral blood flow velocity(BFV).Methods Totally 74 CV patients were assigned into equal group according to a random number table method,in addition to injection of vinpocetine,and treatment group received muscle relaxation and bone-setting techniques. Treated for 20 days,the key observation was symptom score,pain visual analogue score(VAS),mean blood velocity of anterior cerebral artery(ACA),middle cerebral artery(MCA),and posterior cerebral arteries(PCA),vertebral artery(VA);plasma neuropeptide Y(NPY),endothelin-1(ET-1),calcitonin gene-related peptide(CGRP),as well as curative effects between groups before and after treatment.Results The total effective rates were better in treatment group than in control group[91. 89%(34/37)vs 67. 57%(25/37),(P< 0. 05),respectively]. After treatment,symptom(vertigo,headache,nausea and vomiting,stiff neck)scores in groups were decreased(P< 0. 05),which in treatment group were significantly decreased(P< 0. 05);VAS in groups was lower(P< 0. 05),which was lower notably in treatment group(P< 0. 05);mean blood velocity of MCA,ACA,PCA,VA in groups were increased(P< 0. 05),which were increased in treatment group than in control group(P< 0. 05);NPY and ET-1 in groups were decreased(P< 0. 05),which were decreased in treatment group than in control group(P< 0. 05);CGRP in groups was increased(P< 0. 05),which was increased in treatment group than in control group( P< 0. 05).Conclusion For CV patients,muscle relaxation and bone-setting techniques is capable of increasing cerebral artery BFV,improving the symptoms of vertigo,headache,nausea and vomiting,stiff neck and the curative effect.更多还原