【摘要】 目的了解柳州地区手足口病患儿的病原学特征,为手足口病患者的防治提供理论依据。方法回顾性分析2014年1月至2017年12月在柳州市妇幼保健院住院的2 337例手足口病患儿的基本情况及其病原学特征,并进行统计学分析。结果患儿男女比例为1.6:1,且以0～3岁为主,1～2岁年龄段患儿占比最高;手足口病主要由普通肠道病毒(EV)、肠道病毒71型(EV71)及柯萨奇病毒(CA16)感染引起,阳性率分别为91.80%、15.75%、5.05%;与EV阳性率比较,EV-71阳性率及CA-16阳性率相对较低,差异均有统计学意义(P<0.05);且EV-71及CA-16的发病率则偶数年明显高于奇数年,差异具有统计学意义(P<0.05);手足口病主要集中在每年的春夏两季,其中5～6月份为最高峰。结论柳州地区手足口患儿病原学特征与人群、年份、季节相关,可根据其流行特征做好相应防控工作以减少患病机率。更多还原

【Abstract】 Objective To investigate the etiological characteristics of children with hand foot mouth disease(HFMD) in Liuzhou area, and to provide theoretical basis for the prevention and treatment of HFMD. Methods The basic situation and etiological characteristics of 2 337 hand-foot-mouth children, who hospitalized in Liuzhou Maternal and Child Health Hospital from January 2014 to December 2017, were retrospectively analyzed, and the results were statistically analyzed. The data were processed by SPSS17.0 statistical software. Results In this study, the male-female ratio was(1.6:1), with 0-3 years as the main age group and 1-2 years as the highest. HFMD in this area was mainly caused by common enterovirus(EV), enterovirus 71(EV71) and coxsackie virus(CA16), with positive ratios of 91.80%, 15.75%,and 5.05%, respectively; the positive rates of EV-71 and CA-16 were lower than that of EV(P<0.05); the incidence of EV-71 and CA-16 were higher in even years than in odd years(P<0.05). The data of this study showed that HFMD was mainly concentrated in spring and summer of each year, with the peak in May to June. Conclusion The etiology of HFMD in Liuzhou is related to the population, year and season, so we can take prevention and control measures according to its epidemic characteristics to reduce the incidence of HFMD.更多还原