【摘要】 目的探讨再灌注治疗时代急性心肌梗死(AMI)患者住院期间新发心房颤动的危险因素。方法回顾性分析490例行急诊冠状动脉介入治疗的AMI患者的临床资料,按住院期间是否新发心房颤动将患者分为观察组(新发心房颤动)51例和对照组(无新发心房颤动)439例。比较两组的基本资料、生化指标、心脏彩超指标及冠状动脉介入治疗结果,分析AMI患者住院期间新发心房颤动的危险因素。结果 Logistic回归分析结果显示,血浆N末端B型利钠钛前体(NT-proBNP)水平升高及冠状动脉Gensini评分升高是AMI患者住院期间新发心房颤动的危险因素(均P<0.05)。结论高水平的血浆NT-proBNP及高冠脉Gensini评分是行急诊冠状动脉介入治疗的AMI患者住院期间新发心房颤动的危险因素,临床中加强对这类患者的监测,及早发现、及早治疗,降低AMI患者的病死率,改善预后。更多还原

【Abstract】 Objective To investigate the risk factors for new-onset atrial fibrillation during hospitalization in patients with acute myocardial infarction(AMI) in the reperfusion therapy era. Methods The clinical data of 490 AMI patients undergoing emergency percutaneous coronary intervention were analyzed retrospectively, and the patients were divided into observation group(51 cases of new-onset atrial fibrillation) and control group(439 cases without new-onset atrial fibrillation) according to the occurrence of new-onset atrial fibrillation during hospitalization. The baseline data, biochemical indicators, color Doppler echocardiography indicators, and the findings of percutaneous coronary intervention were compared between the two groups. The risk factors for new-onset atrial fibrillation were analyzed among patients with AMI during hospitalization. Results The results of Logistic regression analysis revealed that elevated plasma level of N-terminal pro-B-type natriuretic peptide(NT-proBNP) and higher coronary Gensini score were the risk factors for new-onset atrial fibrillation in patients with AMI during hospitalization(all P<0.05). Conclusion High-level plasma NT-proBNP and increased coronary Gensini score are the risk factors for in-hospital new-onset atrial fibrillation in AMI patients undergoing emergency percutaneous coronary intervention. Clinically, it is necessary to strengthen the monitoring of such patients, achieve diagnosis and treatment as soon as possible, reduce mortality and improve prognosis in patients with AMI.更多还原