【摘要】 骨质疏松症(osteoporosis, OP)是一种人体骨骼损伤和代谢异常的慢性疾病，OP骨折是当前人口老龄化时期面临的主要健康问题，骨折与骨强度相关，不同部位OP骨折发生过程中骨皮质和骨小梁发挥的作用不同，基于定量CT非骨密度测量指标可预测骨折的风险。相比于双能X线吸收测量仪(dual energy X-ray absorptiometry, DXA),定量CT是一种真正三维测量容积骨密度的方法。此文就定量CT技术衍生的有限元分析和计算解剖学预测髋部和脊柱OP骨折的能力进行综述。更多还原

【Abstract】 Osteoporosis(OP) is a chronic disease characterized by bone damage and metabolic abnormalities. OP fracture is a major health problem in the aging of population at present. Fracture is related to bone strength. Bone cortex and bone trabecula play different roles in different sites of OP fracture. Non-bone mineral density measurement based on quantitative CT can predict the risk of fracture. Compared with dual energy X-ray absorptiometry(DXA), quantitative CT is a real three-dimensional method to measure volumetric bone mineral density. The measurement indexes of non-bone mineral density mainly include the related indexes derived from finite element analysis and computational anatomy. This article reviews the ability of finite element analysis and computational anatomy derived from quantitative CT to predict OP fractures of the hip and spine.更多还原