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长期大剂量饮用单味山楂对高脂肪饮食导致的非酒精性脂肪肝患者血脂的影响
Pharmacologic Analysis of Long-term High Dose Single Herb Hawthorn on Blood Lipids in Patients with Nonalcoholic Fatty Liver Disease Caused by High Fat Diet
【摘要】 目的探讨长期大剂量饮用单味药山楂对高脂肪饮食导致的非酒精性脂肪肝患者血脂的影响及药理分析。方法选取2019年9月—2020年9月在沈阳市第六人民医院就诊的60非酒精性脂肪肝患者,均由高脂肪饮食导致,按照随机数字表法分组。对照组30例给予常规治疗,试验组30例在常规疗法基础上长期大剂量饮用单味药山楂进行治疗,比较2组患者的血脂情况以及临床有效率。结果 2组患者患者血脂情况比较,试验组HDL-C、LDL-C、TG、TC均优于对照组,差异有统计学意义(P <0.05);试验组临床总有效率为93.33%,高于对照组临床有效率为76.67%,试验组高于对照组,差异有统计学意义(P <0.05)。结论长期大剂量饮用单味药山楂对高脂肪饮食导致的非酒精性脂肪肝患者可以降低其血脂,提高临床有效率。
【Abstract】 Objective To investigate the effect of long-term high-dose consumption of hawthorn single-herb medicine on blood lipid and pharmacological analysis in patients with non-alcoholic fatty liver disease caused by high-fat diet. Methods A total of 60 patients with nonalcoholic fatty liver disease admitted to the Sixth People’s Hospital of Shenyang from September 2019 to September 2020 were selected,all of whom were caused by high-fat diet and grouped according to the random number table method. 30 patients in the control group received conventional treatment,and 30 patients in the experimental group received long-term high-dose drinking single-herb hawthorn for treatment.The blood lipid status and clinical effective rate of patients in the two groups were compared. Results Compared with the control group,HDL-C,LDL-C,TG and TC in the experimental group were all better than those in the control group,and the difference was statistically significant( P < 0. 05). The clinical effective rate of the experimental group was 93. 33%,and that of the control group was 76. 67%,the clinical effective rate of the experimental group was higher than that of the control group,and there had statistical difference( P < 0. 05).Conclusion Long-term consumption of single herb hawthorn can reduce blood lipid and improve clinical efficiency in patients with nonalcoholic fatty liver disease caused by high-fat diet.
【Key words】 hawthorn; accumulation; high fat diet; nonalcoholic fatty liver disease;
- 【文献出处】 光明中医 ,Guangming Journal of Chinese Medicine , 编辑部邮箱 ,2021年12期
- 【分类号】R575.5
- 【被引频次】6
- 【下载频次】299