【摘要】 目的探讨彩色多普勒超声(CDFI)在非动脉炎性前部缺血性视神经病变(NAION)患者颈动脉、眼球后血管血流参数检测中的价值。方法选取我院收治的NAION患者80例作为NAION组,另选80例无眼部相关疾病的志愿者作为对照组;采用CDFI检测两组研究对象的颈内动脉血流参数、颈内动脉血管弹性参数、眼球后动脉血流参数,采用相干光层析血管成像术检测两组的视杯视盘直径比、黄斑神经节细胞复合体厚度、视盘视网膜神经纤维层厚度;采用简单线性相关Pearson相关分析法分析颈内动脉血流参数、颈内动脉血管弹性参数、眼球后动脉血流参数与NAION病变的关系。结果 NAION组颈内动脉舒张期峰值流速值低于对照组(P<0.05),NAION组颈内动脉RI、IMT值高于对照组(P<0.05);NAION组颈内动脉动脉扩张性、动脉紧张度、压力-应变性系数值低于对照组(P<0.05);NAION组眼动脉动脉的收缩期峰值流速、舒张期峰值流速测定值低于对照组(P<0.05);NAION组眼动脉的RI测定值高于对照组(P<0.05);NAION组的水平及垂直视杯视盘直径比、黄斑神经节细胞复合体厚度均低于对照组(P<0.05)。EDV值与水平及垂直视杯视盘直径比、黄斑神经节细胞复合体厚度呈正相关(P<0.05),RI值与水平及垂直视杯视盘直径比、黄斑神经节细胞复合体厚度呈负相关(P<0.05)。结论 NAION患者颈动脉、眼球后血管血流参数常发生显著改变,并且与NAION患者眼部病变程度有一定的关系。更多还原

【Abstract】 Objective To explore the value of color Doppler ultrasound(CDFI) in the detection of blood flow parameters of carotid artery and retro-ocular vascular in patients with non-arteritic anterior ischemic optic neuropathy(NAION). Methods Eighty NAION patients admitted to our hospital were selected as the NAION group and 80 volunteers without eye-related diseases as the control group. CDFI was used to detect the internal carotid artery blood flow parameters, internal carotid artery vascular elasticity parameters, and eyeballs of the two groups of subjects. The posterior arterial blood flow parameters were measured by coherent optical tomography to detect the optic disc diameter ratio, macular ganglion cell complex thickness, and optic disc retinal nerve fiber layer thickness in the two groups. Simple linear correlation Pearson correlation analysis method was used Analyze the relationship between internal carotid artery blood flow parameters, internal carotid artery vascular elastic parameters, posterior arterial blood flow parameters and NAION lesions. Results The Vd value of the internal carotid artery in the NAION group was lower than that of the control group(P<0.05). The RI and IMT values of the internal carotid artery in the NAION group were higher than those in the control group(P<0.05). The dilatation, arterial tension, and pressure of the internal carotid artery in the NAION group-The strain coefficient value was lower than the control group(P<0.05). The measured values of Vs and Vd of the OA artery in the NAION group were lower than the control group(P<0.05). The measured value of arterial RI was higher than the control group(P<0.05). The horizontal and vertical optic disc diameter ratio and the thickness of the macular ganglion cell complex in the NAION group were lower than those of the control group(P<0.05). EDV value was significantly positively correlated with the ratio of the optic disc diameter of the horizontal and vertical optic cups, the thickness of the macular ganglion cell complex(P<0.05). The RI value was significantly correlated with the ratio of the optic disc diameter of the horizontal and vertical optic cups, and the macular nerve The thickness of the ganglion cell complex was significantly negatively correlated(P<0.05). Conclusion The blood flow parameters of the carotid artery and posterior blood vessels of NAION patients often have significant changes. There is a certain relationship with the degree of ocular lesions in NAION patients.更多还原