【摘要】 目的:对比分析发生于不同部位的骨原发性非霍奇金淋巴瘤(PNLB)的影像表现。方法:搜集经手术病理及免疫组化证实的25例PNLB患者,按照病变发生部位分为四肢骨组(13例)和躯干骨组(12例)。对两组的患者发病年龄、骨质破坏类型、软组织肿块大小及包绕骨病变形式、MRI信号特点进行分析。结果:四肢骨组的患者发病年龄(中位年龄44岁)较躯干骨组(中位年龄54岁)年轻。在四肢骨组中,以单发病变多见(77%),骨质破坏以溶骨性和混合性破坏为主(各占46%,6/13);在躯干骨组中,骨质破坏类型以溶骨性为主(50%),两组的骨质破坏类型差异无统计学意义(P>0.05)。两组中以出现软组织肿块多见(72%),但四肢骨组中软组织肿块偏大,呈环绕型生长。MRI信号特点无特异性。结论:四肢骨组中,患者发病年龄相对年轻,骨质破坏以溶骨性和混合性破坏为主,单发病变多见,周围软组织肿块较躯干骨组大,且呈环周包绕性生长。躯干骨组中,患者发病年龄相对较大,骨质破坏类型以溶骨性为主,周围软组织肿块相对偏小,但也呈环绕型生长。更多还原

【Abstract】 Objective:The purpose of this study was to comparatively analyze the imaging features of primary non-Hodgkin lymphoma(PNLB) of bone in different locations.Methods:25 patients with primary non-Hodgkin lymphoma confirmed by pathology were included in this study from 2004 to 2005.According to the location,the cases were divided into two groups:limb bone group(13 cases) and trunk bone group(12 cases).The age,type of bone destruction,soft tissue mass,signal pattern of the two groups were analyzed.Results:The age of limb bone group(median age 44 yo) was younger than that of the trunk bone group(median age 54 yo).Single lesion was more common in the limb bone group(77%),and osteolytic bone destruction and mixed bone destruction was more common(46%,respectively).In the trunk bone group,osteolytic bone destruction was the main type of bone destruction(50%),and there was no significant difference between the two groups(P>0.05).Although the soft tissue mass was more common in the two groups(72%),the size of soft tissue mass in the limb bone group was larger with a surrounding growing pattern.MRI signal characteristics were not specific.Conclusion:In the limb bone group,patients with primary non Hodgkin’s lymphoma of bone are relatively young;bone destruction was mainly osteolytic and mixed destruction;single lesion was more common,and the size of soft tissue mass was larger.While in the trunk bone group,the age was older;soft tissue mass was smaller with a surrounding growing pattern.更多还原