【摘要】 为评价复方阿莫西林乳房注入剂对泌乳期奶牛临床型乳房炎的治疗效果,在甘肃某两个牛场选择70头自然发生的临床型乳房炎奶牛进行临床试验。将患病奶牛随机分为试验组(n=36头)和对照组(n=34头)。试验用药和对照用药分别为郑州百瑞动物药业有限公司和齐鲁动物保健品有限公司提供的复方阿莫西林乳房注入剂。每个感染乳区注入3 g药物,每12 h注射1次,连续用药3 d。在用药前、停药后7 d及14 d采集各组奶牛的奶样进行细菌学检测及乳汁体细胞计数。通过临床观察、细菌清除率及体细胞计数变化对临床疗效进行评价。停药后14 d,试验组和对照组的临床治愈率分别为58.3%和61.8%,细菌总清除率分别为94.12%和93.55%。两组奶样中的SCC在治疗后均显著下降(P<0.01)。两组临床疗效无统计学差异(P>0.05),表明试验用药对奶牛临床型乳房炎具有良好的治疗效果。更多还原

【Abstract】 A case of newborn calf diarrhea occurred in a large-scale dairy farm in Shaanxi province.In order to determine the cause of the disease, clinical autopsy was performed, aseptic samples were collected for bacterial isolation and identification, and PCR detection of viruses.The disease was finally diagnosed as bovine coronavirus(BCoV),bovine rotavirus(BRV) and Escherichia coli mixed infection.A drug susceptibility test was performed in the isolated E.coli,and the results showed that it was sensitive to levofloxacin and norfloxacin, and resistant to tetracycline, trimethoprim, polymyxin B,kanamycin, gentamicin, doxycycline, ampicillin and spectinomycin.更多还原