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菊苣酸的研究现状与展望

Current status and prospect of research on chicoric acid

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【作者】 吴超丛晓娟高源李健李梓欣田新吕世洁李峰冯帅

【Author】 WU Chao;CONG Xiao-juan;GAO Yuan;LI Jian;LI Zi-xin;TIAN Xin;LYU Shi-jie;LI Feng;FENG Shuai;Shandong University of Traditional Chinese Medicine;Shandong Drug and Food Vocational College;Affiliated Hospital of Shandong University of Traditional Chinese Medicine;Shandong Provincial Collaborative Innovation Center for Traditional Chinese Medicine Quality Control and Construction of Whole Industrial Chain;

【通讯作者】 李峰;冯帅;

【机构】 山东中医药大学山东药品食品职业学院山东中医药大学附属医院山东省高校中药质量控制与全产业链建设协同创新中心

【摘要】 近年来国内外对菊苣酸的研究热度逐年升高,主要研究领域集中在其生物活性与药理作用的探索。本研究团队在菊苣酸的抗病毒研究中,首次发现了其有强效的抗呼吸道合胞病毒活性作用,申请了发明专利并获得了国家科技重大新药创制专项的支持。文章通过统计分析菊苣酸相关文献,全面汇总了菊苣酸的国内外研究进展,讨论了菊苣酸研究的潜在领域与发展方向,以期为菊苣酸的后续开发与研究提供参考。

【Abstract】 In recent years, research on chicoric acid has been on the rise worldwide. The main areas of research have been in its biological activity and pharmacological effect. During the antiviral research of chicoric acid, our team discovered for the first time its potent anti-respiratory syncytial virus(RSV) activity, for which a patent for invention has been applied, and which has gained support by the National Science and Technology Project of Major New Drug Development. This article summarizes the research progress of chicoric acid in and outside of China through statistical analysis of relevant literatures, and discusses the potential research fields and development direction in the future, with a view to providing reference for follow-up development and research.

【基金】 国家重大新药创制专项(N o.2017Z X09301058);山东省医药卫生科技发展计划项目(No.202013030996)~~
  • 【文献出处】 中华中医药杂志 ,China Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2021年12期
  • 【分类号】R284;R285
  • 【被引频次】4
  • 【下载频次】801
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