【摘要】 目的探讨骨旁骨肉瘤的临床病理特征、诊断、鉴别诊断及预后。方法对7例骨旁骨肉瘤进行临床资料、影像学、病理组织形态学分析,并观察其预后。结果男性2例,女性5例,年龄范围35～60岁,平均年龄45.9岁。临床多表现为上肢或下肢缓慢生长的无痛或轻微疼痛的包块,以股骨下段较多。X线显示为骨皮质表面的广基性蘑菇状肿块影。CT显示其中1例复发病例髓腔受累。组织学主要表现为大致平行排列的分化良好的骨小梁和填充于其间的梭形纤维间质伴胶原化构成。结论骨旁骨肉瘤是一种位于骨表面的低度恶性成骨性肿瘤,好发于长骨干骺端,特别是股骨下段,预后较好。骨旁骨肉瘤的诊断及鉴别诊有赖于临床、影像学及病理组织学的三结合,正确的诊断及治疗可以改善或提高其预后。更多还原

【Abstract】 Objective To evaluate the clinicopathologic features, diagnosis, differential diagnosis and prognosis of parosteal osteosarcoma.Methods Seven cases of parosteal osteosarcoma were analyzed for their clinical data, radiological and pathological histomorphology.Results Among 7 cases, there were 2 males, 5 females, and age range was 35-60 years old, with average age of 45.9. Clinical manifestation was the slow growth of upper or lower package with no pain or mild pain, with the popliteal fossa the most common. X-ray showed extensive cortical surface of a mushroom-shaped mass. In one relapsed case, CT examinations showed marrow involvement. Histology showed more or less parallel arrangement of well-differentiated trabecular bone filling in the spindle-shaped fibrous stroma.Conclusion Parosteal osteosarcoma is a low-grade malignant bone tumor located on the surface of the bone. It is more likely to occur in the metaphysis of the long bone, especially the lower femur, with a good prognosis. Diagnosis and differential diagnosis of parosteal osteosarcoma depends on the combination of clinical data, radiological and pathological histomorphology. The correct diagnosis and treatment can improve or enhance the prognosis.更多还原