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推拿联合经颅重复针刺法为主针刺治疗轻中度失眠的随机对照临床研究

Randomized Controlled Clinical Study on the Treatment of Mild and Moderate Insomnia by Acupuncture Combined with“Transcranial Repetitive Acupuncture”

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【作者】 张天羽李同军

【Author】 ZHANG Tianyu;LI Tongjun;Heilongjiang University of Traditional Chinese Medicine;The Second Affiliated Hospital of Heilongjiang Traditional Chinese Medicine University;

【通讯作者】 李同军;

【机构】 黑龙江中医药大学黑龙江中医药大学附属第二医院

【摘要】 目的:观察推拿联合经颅重复针刺法为主针刺治疗轻中度失眠的临床疗效。方法:将符合标准的60例轻中度失眠患者随机分为2组,即观察组30例、对照组30例。观察组给予推拿联合经颅重复针刺法为主针刺治疗。对照组给予艾司唑仑片口服治疗。2组疗程均为4周。记录并比较2组治疗前、治疗后日觉醒次数、日总睡眠时间;采用匹兹堡睡眠质量指数(PSQI)量表评价睡眠质量;采用抑郁自评量(SDS)与焦虑自评量表(SAS)评价焦虑、抑郁情绪;采用酶联免疫吸附法测定血清5-HT、NE水平。结果:治疗后,2组日觉醒次数、日总睡眠时间、睡眠质量、SAS评分、SDS评分较治疗前均显著改善,组内治疗前后比较差异具有统计学意义(P<0.01);观察组日觉醒次数、睡眠质量、SAS评分、SDS评分较对照组明显减少,组间比较差异具有统计学意义(P<0.01);观察组日总睡眠时间较对照组明显增加,2组比较差异具有统计学意义(P<0.01)。治疗后,2组血清5-HT、NE含量较治疗前均显著增加(P<0.01);观察组血清5-HT、NE含量较对照组明显增加,2组比较差异具有统计学意义(P<0.01)。结论:推拿联合经颅重复针刺法为主针刺治疗轻中度失眠临床疗效肯定,可以临床推广使用。

【Abstract】 Objective:To observe the clinical efficacy of massage combined with transcranial repetitive acupuncture for the treatment of mild to moderate insomnia.Methods:Sixty patients with mild to moderate insomnia who met the criteria were randomly divided into 2 groups,namely,30 in the observation group and 30 in the control group.The observation group was given massage combined with transcranial repetitive acupuncture as the main acupuncture treatment.The control group was given estazolam tablets orally.The course of treatment in both groups was 4 weeks.Record and compare the number of daily awakenings and total daily sleep time of the two groups before and after treatment;use the Pittsburgh Sleep Quality Index (PSQI) scale to evaluate sleep quality;use the self-rating depression scale (SDS) and the self-rating anxiety scale (SAS) Evaluate anxiety and depression;use enzyme-linked immunosorbent assay to measure serum 5-HT and NE levels.Results:After treatment,the number of daily awakenings,total daily sleep time,sleep quality,SAS score,and SDS score in the two groups were significantly improved compared to before treatment.The difference between before and after treatment was statistically significant (P<0.01);The number of awakenings,sleep quality,SAS score,and SDS score were significantly reduced compared with the control group,and the difference between the groups was statistically significant (P<0.01);the total daily sleep time of the observation group was significantly increased compared with the control group,and the difference between the two groups was statistically significant Significance (P<0.01).After treatment,the levels of serum 5-HT and NE in the two groups were significantly increased compared with those before treatment (P<0.01);the levels of serum 5-HT and NE in the observation group were significantly increased than those in the control group,and the difference between the two groups was statistically significant (P<0.01).Conclusion:Tuina combined with transcranial repetitive acupuncture is the main acupuncture method to treat mild to moderate insomnia with a positive clinical effect and can be used clinically.

【关键词】 失眠推拿针刺睡眠质量单胺类递质
【Key words】 InsomniaMassageAcupunctureSleep qualityMonoamine transmitter
【基金】 孙远征全国名老中医药专家传承工作室项目(国中医药人教发[2014]20号)
  • 【文献出处】 中医药临床杂志 ,Clinical Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2021年01期
  • 【分类号】R246.6
  • 【下载频次】163
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