【摘要】 目的探讨经皮冠状动脉介入(PCI)治疗对冠心病多支血管病变病人生存质量的影响。方法选取2016年1月—2017年5月接受治疗的187例冠心病多支血管病变病人,均符合临床诊断标准。按照随机数字表法分为观察组(94例)与对照组(93例)。对照组采用常规药物治疗,观察组在对照组的基础上完成PCI治疗。比较两组治疗前及治疗后3个月西雅图心绞痛问卷(SAQ)评分及健康调查表(SF-36)评分变化;随访1年,记录两组病人不良心血管事件(MACE)的发生情况。结果治疗后3个月,两组SAQ及SF-36各维度评分均明显高于治疗前(P<0.01);且观察组治疗后SAQ中3个维度(心绞痛稳定状态、心绞痛发作情况、治疗满意度)及SF-36中5个维度(身体疼痛、活力、生理职能、精神健康、社会功能)评分均明显高于对照组(P<0.05);随访1年,观察组病人MACE发生率为12.8%,明显低于对照组的24.7%(P<0.05)。结论 PCI治疗能够明显提高冠心病多支血管病变病人的生存质量,降低MACE的发生率。更多还原

【Abstract】 Objective To investigate the effect of percutaneous coronary intervention(PCI) on quality of life in patients with multivessel vascular coronary heart disease(CHD). Methods One hundred and eighty-seven patients with multivessel vascular CHD who were treated in our hospital from January 2016 to May 2017 were selected and divided into observation group(n=94) and control group(n=93),according to random number table method.The patients in control group were treated with conventional medicine,the patients in observation group were treated with PCI on the basis of control group.The Seattle Angina Questionnaire(SAQ),SF-36 score were compared before treatment and 3 months after treatment between two groups.The adverse cardiac events in both groups were recorded during one-year follow-up.Results Three months after treatment,the scores of SAQ and SF-36 in both groups were significantly higher than those before treatment(P<0.01).The 3 dimensions of SAQ after treatment in observation group(stable state of angina pectoris,attack of angina pectoris,treatment satisfaction),and the scores of 5 dimensions(body pain,vitality,physiological function,mental health,social function) in SF-36 were significantly higher than those in control group(P<0.05).The incidence of adverse cardiac events in observation group was significantly lower than that in control group(12.8% vs 24.7%,P<0.05).Conclusion Compared with drug therapy,PCI can significantly improve the quality of life and reduce the incidence of adverse cardiac events in patients with multivessel vascular coronary heart disease.更多还原