【摘要】 目的:探讨中西医结合治疗缺血性脑卒中的疗效及对血脂、血液流变学及炎症因子的影响。方法:将160例缺血性脑卒中患者随机分为观察组和对照组,观察组进行中西医结合治疗,对照组进行西医治疗,比较观察组(80例)和对照组(80例)患者的临床疗效、中医证候、血脂浓度、血液流变学及炎症因子的差异。结果:治疗后,观察组的总有效率明显高于对照组,两组比较差异具有统计学意义(χ2=7.500,P=0.006);两组各症状评分均较治疗前变化明显(P <0.05),且观察组各证候积分下降更为显著(P <0.05);两组患者的总胆固醇、甘油三酯、低密度脂蛋白浓度较治疗前均有所下降(P <0.05);观察组下降更为明显(P <0.05),两组患者高密度脂蛋白均升高(P <0.05),观察组升高明显(P <0.05);两组全血高切粘度、全血低切粘度、血浆粘度、血细胞比容(Hematocrit,HCT)和红细胞沉降率(Erythrocyte Sedimentation Rate,ESR)较治疗前均有不同程度降低,观察组全血高切粘度、全血低切粘度、血浆粘度、HCT和ESR均明显低于对照组;两组各指标均较治疗前有所下降(P <0.05);观察组各炎症因子水平下降更为明显(P <0.05)。结论:中西医结合治疗缺血性脑卒中可明显缓解患者临床症状,减轻炎症反应、降低患者中医证候和血脂水平、改善患者血液流变学,具有较高的临床推广价值。更多还原

【Abstract】 Objective: To investigate the effects of the integrative medicine on ischemic stroke and blood lipids, hemorheology and inflammatory factors. Methods: 160 patients were randomly divided into the observation and control groups. The observation group was treated in integrative medicine, the control group was treated in western medicine. Results: After treatment, the total effective rate in the observation group was significantly higher than that in the control group, the difference between the two groups was statistically significant(χ~2=7.500, P=0.006). The symptom scores in the two groups were significantly decreased than before treatment(P<0.05), and the scores of the syndromes in the observation group were decreased more significantly(P<0.05). The total cholesterol, triglycerides and low-density lipoprotein concentrations in the two groups were decreased compared to before treatment(P<0.05). The high-density lipoprotein in the two groups were increased(P<0.05), and the observation group increased more significantly(P<0.05). The HSV, LSV, plasma viscosity, HCT and ESR in the observation group were significantly lower than those in the control group, the indexes in the two groups were lower than before treatment(P<0.05), the inflammatory factors in the observation group were dropped more obviously(P<0.05). Conclusion: The treatment of ischemic stroke in the integrative medicine can significantly relieve the clinical symptoms of patients, reduce inflammation, reduce the TCM syndromes and blood lipid levels, and improve the blood rheology of patients. It has high clinical promotion value.更多还原