【摘要】 目的:调查韶关市仁化县2016-2019年慢性萎缩性胃炎(CAG)发病情况及相关因素。方法:回顾性分析本地区2016年1月-2019年11月行胃肠镜和胃黏膜检查的2 051例患者的临床资料,分析CAG发病情况以及流行特点,分析其发生的危险因素。结果:2016-2019年分别调查的487、512、533、519例行胃肠镜和胃黏膜检查的患者中分别有92、101、109、102例发生CAG,发生率分别为18.89%、19.73%、20.45%、19.65%;不同民族、胃癌家族史、吃饭快速状态、是否喜食腌制食品、是否喜食油炸食品患者CAG发生率比较,差异均无统计学意义(P>0.05);男性、年龄>60岁、幽门螺杆菌感染阳性、吸烟史、酗酒史、饮食不规律、食用烫食、消化不良症候群、胃酸返流症候群、消化性溃疡患者CAG发生率高于其他患者(P<0.05);logisitic回归分析显示,性别、年龄、BMI指数、吸烟、酗酒、饮食不规律、食用烫食、消化不良症候群、胃酸返流症候群、消化性溃疡是CAG发生的危险因素(P<0.05)。结论:CAG的发生与性别、年龄、生活习惯等多种因素有关,应针对这些危险因素制定有效的预防措施,有效减缓CAG向早癌发展,改善患者预后。更多还原

【Abstract】 Objective:To investigate the incidence and related factors of chronic atrophic gastritis (CAG) in Renhua County of Shaoguan City from 2016 to 2019.Method:The clinical data of 2 051 patients who underwent gastroenteroscopy and gastric mucosa examination from January 2016 to November 2019 were analyzed retrospectively.The incidence and epidemic characteristics of CAG were analyzed,and the risk factors were analyzed.Result:Among 487 cases,512 cases,533 cases and 519 cases of gastroenteroscopy and gastric mucosa examination investigated from 2016 to 2019,92 cases,101 cases and 109 cases had CAG,with the incidence of 18.89%,19.73%,20.45% and 19.65% respectively.There were no statistically significant differences in CAG incidence among different ethnic groups,family history of gastric cancer,fast eating status,liking to eating pickled food or not,or preference for oil-fried food (P>0.05).The incidence of CAG in patients with male,age > 60 years old,Helicobacter pylori infection,smoking history,alcohol history,irregular diet,eating hot food,dyspepsia syndrome,gastric acid reflux syndrome and peptic ulcer were higher than those in other patients (P<0.05).Logisitic regression analysis showed that sex,age,BMI,smoking,alcohol abuse,irregular diet,eating hot food,pickled food preference,dyspepsia syndrome,acid reflux syndrome,and peptic ulcer were risk factors for CAG (P<0.05).Conclusion:The occurrence of CAG is related to gender,age,lifestyle and other factors,so effective preventive measures should be formulated for these risk factors to effectively slow down the occurrence of CAG to early cancer and improve the prognosis of patients.更多还原