【摘要】 目的:探讨超声电导经皮给药辅助治疗恶性肿瘤并发肺部感染的临床效果及护理成效。方法:选择2018年1月-2019年10月本院收治的已确诊的恶性肿瘤并发肺部感染患者80例。按照随机数字表法将其分为对照组和观察组,每组40例。对照组给予常规抗感染治疗,观察组在对照组基础上加用超声电导经皮给药辅助治疗。比较两组的临床疗效、临床症状及影像学检查恢复正常时间、血清学炎症指标、抗生素平均使用时间、平均住院时间及不良反应发生情况。结果:观察组治疗总有效率为92.50%,显著高于对照组75.00%,差异有统计学意义(P<0.05)。观察组咳嗽停止时间、体温恢复正常时间、肺部啰音消失时间及胸片检查恢复正常时间均短于对照组,差异均有统计学意义(P<0.05)。治疗后,两组的PCT、CRP和WBC均低于治疗前,且观察组均低于对照组,差异均有统计学意义(P<0.05)。观察组抗生素使用时间和平均住院时间均短于对照组,差异均有统计学意义(P<0.05)。两组不良反应发生情况比较,差异无统计学意义(P>0.05)。结论:超声电导经皮给药辅助治疗能提高肿瘤并发肺部感染的临床效果,加快患者临床症状恢复正常,降低炎症水平,同时不增加不良反应。更多还原

【Abstract】 Objective:To explore the clinical effect and nursing effect of ultrasound guided percutaneous drug delivery in the treatment of malignant tumor complicated with pulmonary infection.Method:A total of 80 patients with confirmed malignant tumor complicated with pulmonary infection admitted to our hospital from January 2018 to October 2019 were selected.They were divided into control group and observation group according to the random number table method,40 cases in each group.The control group received routine anti-infective treatment,the observation group in the control group on the basis of transdermal ultrasound guided drug delivery adjuvant treatment.The clinical efficacy,clinical symptoms and the recovery time of imaging examination,serological inflammatory indexes,the average time of antibiotics use,the average length of stay and the occurrence of adverse reactions of the two groups were compared.Result:The total effective rate of the observation group was 92.50%,significantly higher than 75.00% in the control group,the difference was statistically significant (P<0.05).The cough stop time,body temperature recovery time,lung rale disappearance time and chest radiograph recovery time in the observation group were shorter than those in the control group,the differences were statistically significant (P<0.05).After treatment,PCT,CRP and WBC in the two groups were lower than those before treatment,and the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).The time of using antibiotics and the average time of hospitalization in the observation group were shorter than those in the control group,the differences were statistically significant (P<0.05).The adverse reactions of the two groups was compared,there was no significant difference (P>0.05).Conclusion:Transcutaneous ultrasound-guided drug delivery can improve the clinical efficacy of tumor complicated with pulmonary infection,accelerate the recovery of clinical symptoms,reduce the level of inflammation,without increasing adverse reactions.更多还原