【摘要】 目的观察不同时间间隔实施输卵管通液术对输卵管堵塞致不孕症患者妊娠率、血液流变学及经济学的影响。方法 96例输卵管堵塞致不孕症患者作为研究对象,按随机数字表法分为对照组和观察组,各48例。对照组患者采用3 d进行1次输卵管通液术治疗,观察组患者采用隔天1次进行输卵管通液术治疗。观察比较两组患者输卵管通畅情况、治疗前后血液流变学指标(血浆粘度、全血粘度、红细胞压积、血沉)水平、1年妊娠率及治疗费用。结果观察组患者输卵管通畅率91.67%高于对照组的64.58%,输卵管阻塞率2.08%、输卵管通而不畅率6.25%低于对照组的12.50%、22.92%,差异均具有统计学意义(P<0.05)。两组患者治疗前血浆粘度、全血粘度、红细胞压积、血沉水平比较,差异无统计学意义(P>0.05);治疗后,两组患者血浆粘度、全血粘度、红细胞压积、血沉水平较治疗前明显降低,且观察组患者血浆粘度、全血粘度、红细胞压积、血沉水平均明显低于对照组,差异具有统计学意义(P<0.05)。观察组患者1年妊娠率81.25%高于对照组的62.50%,治疗费用(503.72±30.82)元少于对照组的(786.85±34.45)元,差异具有统计学意义(P<0.05)。结论在输卵管堵塞致不孕症患者中,采用隔天1次进行输卵管通液术治疗,治疗费用相对较低,可明显改善血流动力学指标,降低血液粘度,提升妊娠率,效果理想。更多还原

【Abstract】 Objective To observe the effect of hydrotubation at different time intervals on pregnancy rate, hemorheology and economics of patients with infertility caused by tubal obstruction. Methods A total of 96 patients with infertility caused by tubal obstruction as study subjects were divided into control group and observation group by random numerical table, with 48 cases in each group. The control group was treated with hydrotubation once every 3 d, and the observation group was treated with hydrotubation once every other day. The tubal patency rate, the levels of hemorheology indexes(plasma viscosity, whole blood viscosity, hematocrit, erythrocyte sedimentation rate) before and after treatment, 1-year pregnancy rate and treatment cost were observed and compared between the two groups. Results The tubal patency rate 91.67% of the observation group was higher than that of the control group 64.58%, tubal obstruction rate 2.08% and partial tubal obstruction rate 6.25% were lower than that of the control group 12.50% and 22.92%, and the difference was statistically significant(P<0.05). Before treatment, there was no statistically significant difference in plasma viscosity, whole blood viscosity, hematocrit, erythrocyte sedimentation rate between the two groups(P>0.05). After treatment, the plasma viscosity, whole blood viscosity, hematocrit, erythrocyte sedimentation rate of the two groups was obviously lower than that before treatment, and the observation group was obviously lower than the control group, and the difference was statistically significant(P<0.05). The 1-year pregnancy rate 81.25% of the observation group was higher than that of the control group, and treatment costs(503.72±30.82) yuan was less than that of the control group(786.85±34.45) yuan, and the difference was statistically significant(P<0.05). Conclusion In patients with infertility caused by tubal obstruction, the treatment cost of hydrotubation every other day is relatively low, and it can significantly improve hemodynamic indicators, reduce blood viscosity, and increase pregnancy rate. The effect is ideal.更多还原