【摘要】 目的研究神经内镜下大脑半球离断术的有效性和安全性。方法回顾性分析1例药物难治性癫■病人的临床资料,采用神经内镜下大脑半球离断术,分析其术后疗效和并发症。结果术后MRI提示左侧基底核区与周围脑叶完全离断,DTI提示各脑叶与基底核区无纤维传导束联系。术后2周内有发热,予腰大池置管引流后控制;无其他并发症。随访6个月,无癫■发作,达Engel Ⅰ级;神经认知功能较术前改善。结论对药物难治性癫■行神经内镜下大脑半球离断术安全、微创、有效。更多还原

【Abstract】 Objective To study the efficacy and safety of endoscopic cerebral hemisphere devascularization for drug-refractory epilepsy.Methods Clinical data of 1 patient with drug-refractory epilepsy undergoing endoscopic devascularization of the cerebral hemisphere were analyzed retrospectively. The postoperative efficacy and complications were analyzed. Results Postoperative MRI showed that the left basal ganglia was completely disconnected from the surrounding brain lobes, and diffusion tensor imaging(DTI) also showed that there was no connection between the brain lobes and basal ganglia. Fever occurred 2 weeks after the operation, and was controlled after lumbar drainage, and no other complications occurred. During a follow-up period of 6 months, the patient obtained seizure free(Engel grade Ⅰ) with neurocognitive functional improvement compared with preoperation. Conclusion Endoscopic devascularization of the cerebral hemisphere is minimally invasive, safe and effective for drug-refractory epilepsy.更多还原