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精准医学时代的乳腺癌个体化治疗选择

Individualized treatment options for breast cancer in the era of precision medicine

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【作者】 沈乐桑姜晶鑫潘唯玮陈武臻黄建

【Author】 SHEN Lesang;JIANG Jingxin;PAN Weiwei;CHEN Wuzhen;HUANG Jian;Department of Breast Surgerythe Second Affiliated Hospital,Zhejiang University School of MedicineKey Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province,Hangzhou 310009,China;Department of Breast Surgerythe Second Affiliated Hospital,Zhejiang University School of MedicineKey Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province;

【通讯作者】 黄建;

【机构】 浙江大学医学院附属第二医院乳腺外科浙江省肿瘤微环境与免疫治疗重点实验室

【摘要】 人类基因组计划以及肿瘤基因组计划拉开了精准医学时代的序幕,其本质是利用生物信息学、遗传学等技术,并整合患者临床资料,为不同生物学特征的患者提供精准化诊治。随着测序技术的发展,乳腺癌的精准治疗已逐渐渗透到肿瘤分子分型、靶向治疗以及外科手术等各个方面,以指导个体化的临床决策和治疗选择。

【Abstract】 The Human Genome Project and the Cancer Genome Atlas have unlocked a new era of precision medicine. Its essence is the use of technology such as bioinformatics and genetics,combined with patients’ clinical information,to provide accurate treatment for patients with different biological characteristics.With the development of sequencing technology, precision treatment of breast cancer has gradually penetrated into molecular typing,targeted therapy,surgical treatment and other means,facilitating individualized clinical decisions and treatment options.

【基金】 省部共建重大项目(WKJ-ZJ-1803)
  • 【文献出处】 中国肿瘤外科杂志 ,Chinese Journal of Surgical Oncology , 编辑部邮箱 ,2020年04期
  • 【分类号】R737.9
  • 【被引频次】6
  • 【下载频次】515
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