【摘要】 目的分析血液筛查反应性的献血者归队情况。方法选取2018年1月1日至2019年12月31日来浙江省血液中心申请归队的血液筛查反应性献血者进行进一步筛查,献血者标本HBs Ag、抗-HCV、抗HIV、梅毒抗体检测采用ELISA和化学发光法,HBV/HCV/HIV核酸检测采用转录介导扩增技术和实时荧光PCR法。结果共461例献血者申请归队,其中男293例,女168例。申请归队献血者年龄35～45岁最多,164例,占35.6%。归队间隔时间最短180 d,最长8 156 d,中位数为583 d。在418例完成归队流程者中231例允许归队、116例永久屏蔽、71例进入下一轮归队流程。按HBs Ag、抗-HCV、HIV Ag/Ab、抗-TP、核酸联检原因分组,允许归队比例分别为64.2%、59.3%、74.5%、65.2%、33.1%,核酸联检组允许归队比例最低(P<0.05)。结论血液筛查反应性献血者检测后有一定比例的允许归队者,多数可能在屏蔽后的1年半左右申请归队。更多还原

【Abstract】 Objective To analyze the reentry situation of the blood donors with reactive blood testing results. Methods The blood screening reactive donors who applied for reentry from January 2018 to December 2019 in Zhejiang Provincial Blood Center were included in the analysis. HBs Ag, anti HCV, anti HIV and syphilis antibodies were tested by ELISA and chemiluminescence immunoassay, and HBV/HCV/HIV nucleic acid were detected by transcription-mediated amplification and real-time RT-PCR. Results There were 461 subjects came back to the team, including 293 men and 168 women; and 35.6%of whom(n=164) were aged 35-45. The shortest time interval for reentry was 180 d, while the longest was 8156 d with a median of 583 d. Among 418 subjects who completed the reentry process, 231 were allowed to return, 116 were permanently shielded and 71 were for next round. As grouped according to the reasons, the proportion of successful reentry of HBs Ag, anti HCV, HIV Ag/Ab, anti TP and nucleic acid were 64.2%, 59.3%, 74.5%, 65.2% and 33.1%, respectively; and the nucleic acid group was the lowest(P<0.05). Conclusion After blood screening, reactive blood donors are allowed to reentry in a certain proportion. Most of them may participate in the reentry process about one and half years after screening.更多还原