【摘要】 目的观察分析应用局部药物注射的方法辅助治疗耐多药肺结核的临床效果。方法选取我院呼吸科2018年4月至2019年3月接诊的82例耐多药肺结核患者作为研究对象群体,按照其接受的不同治疗方式将其分为两组,其中,普通治疗组应用常规的化疗方法进行疾病的治疗(n=41)辅助治疗组在常规化疗的基础上实施结合纤支镜对患者进行局部注射的方法进行治疗(n=41),观察两组患者在经过一定的治疗阶段后的痰菌转阴率和病灶范围吸收情况,并针对患者出现的不良反应情况进行观察。结果观察可见,辅助治疗组患者的痰菌转阴率和病灶吸收情况均优于普通治疗组(P<0.05),两组患者在治疗不良反应上的对比结果无显著统计学意义(P>0.05)。结论可见应用纤支镜对耐多药肺结核患者实施辅助治疗,能够取得显著的治疗效果,促进病灶范围的吸收,应当在临床治疗中优先选择这种治疗方式实施治疗。更多还原

【Abstract】 Objective to observe and analyze clinical effect of local drug injection in treatment of MDR-TB. Methods choose 82 cases MDR-TB patients received in respiratory department of our hospital from April 2018 to March 2019 as study objects. Divide them into two groups according to different treatment methods. Among them, common treatment group was treated with routine chemotherapy(n=41), auxiliary treatment group with local injection on the basis of routine chemotherapy combined with fiberbronchoscope methods(n=41). Observe sputum negative rate and focus absorption area of two groups after some certain treatment stage, and adverse reactions of two groups. Results observation showed, sputum negative conversion rate and focus absorption in auxiliary treatment group was better than general treatment group(P< 0.05), difference of adverse reactions showed no significance between two groups(P>0.05). Conclusion it can be seen, fiberbronchoscope can achieve significant curative effect in treatment of MDR-TB patients, promote focus area absorption, it is necessary to take it as first choice in clinical treatment.更多还原