【摘要】 滤泡性淋巴瘤(follicular lymphoma,FL)是一种起源于滤泡生发中心B细胞的淋巴瘤,其发病率在美国和西欧最高,而在亚洲和发展中国家的发病率相对较低。FL主要累及淋巴结,通常表现为无痛性多发淋巴结肿大。原发于淋巴结外的FL常见于胃肠道、软组织、乳腺及眼眶附属器。FL患者多表现为惰性临床过程,总生存率较高,但多数患者仍会复发或进展。回顾FL的预后因素,为指导患者的临床治疗提供理论依据。更多还原

【Abstract】 Follicular lymphoma(FL) is a neoplasm derived from follicular center B cells. The incidence rates of FL are highest in America and Western Europe, but are much lower in Asia and developing countries. FL mainly involves lymph nodes, and the patients usually present with painless enlargement of multiple lymph nodes. FL originating from extranodal sites is common in gastrointestinal tract, soft tissues, breast and ocular adnexa. Most patients have an indolent clinical course with a long survival, however, a subset of patients suffer from relapse or progression over years. We reviewed the prognostic factors of FL, in order to provide some theoretical guidance to clinical treatment.更多还原