【摘要】 目的分析广州市3岁以下儿童维生素A水平,评价儿童维生素A营养状况。方法选择2018年11月-2019年4月在广东省妇幼保健院儿童保健门诊常规健康检查的2792名6～30月龄儿童为研究对象;通过LK3000V维生素检测仪电化学法检测血清维生素A水平。结果 6～30月龄儿童平均维生素A水平(0. 63±0. 20)μmol/L; 6月龄组(0. 62±0. 20)μmol/L和12月龄组(0. 63±0. 20)μmol/L均低于24月龄以上组(0. 66±0. 21)μmol/L儿童维生素A水平,差异具有统计学意义(F=4. 117,P=0. 006);总体维生素A缺乏比例33. 1%,其中6月龄组最高(36. 2%),随年龄增加而下降(χ2=4. 564,P=0. 033);维生素A缺乏率随儿童BMI增加呈上升趋势,但差异无统计学意义。结论广州地区3岁以下儿童维生素A缺乏率较高,与年龄呈负相关,应提高对低年龄阶段儿童维生素A缺乏问题的重视。更多还原

【Abstract】 Objective This study was to evaluate the serum vitamin A level among under-three children in Guangzhou. Methods A total of 2792 children aged 6-30 months who received physical examination in children’s health clinic during Nov 2018 to Apr 2019 were selected as subjects. Serum vitamin A levels were measured by electrochemical method using LK3000 V. Results The mean serum vitamin A levels was 0. 63 ± 0. 20 μmol/L. Serum vitamin A in children aged 6 months( 0. 62 ± 0. 20 μmol/L) and in children age 12 months( 0. 63 ± 0. 20 μmol/L) were lower than that in children aged 24 months( 0. 66 ± 0. 21 μmol/L),which showed significant differences( F = 4. 117,P = 0. 006). The overall prevalence of vitamin A deficiency was 33. 1%. The highest prevalence of vitamin A deficiency was found in the 6 months age group( 36. 2%). The prevalence of vitamin A deficiency were decreased with children’s age( χ2= 4. 564,P = 0. 033). The prevalence of vitamin A deficiency had a increased trend with children’s BMI,but there was no significant difference among different groups. Conclusions The prevalence of vitamin A deficiency is high among children under 3 years in Guangzhou,which is negatively correlated with children ’s age. More attention should be payed to vitamin A deficiency,especially in low age group.更多还原