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吲哚菁绿标记荧光预防胃癌术后吻合口瘘的研究

Study on Indocyanine Green-labeled Fluorescence to Prevent Anastomotic Fistula After Gastric Cancer Operation

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【作者】 程翔张军

【Author】 CHENG Xiang;ZHANG Jun;Department of Gastroenterology,the First Affiliated Hospital of Chongqing Medical University;

【通讯作者】 张军;

【机构】 重庆医科大学附属第一医院胃肠外科

【摘要】 胃癌是起源于胃黏膜上皮的恶性肿瘤,近年来胃癌发病率虽在全球范围有所下降,但排名仍然靠前。手术切除是胃癌的主要治疗措施,可明显改善患者预后,但术后易出现并发症,其中吻合口漏是术后胃癌患者常见且严重的并发症,严重影响患者长期生存和预后。吲哚菁绿标记荧光技术通过评估术中吻合口灌注,能改善术后吻合口愈合情况,进一步降低吻合口瘘发病率。本文通过对吻合口瘘的发生、吲哚菁绿标记荧光技术介绍、吲哚菁绿标记荧光技术在胃癌术中的应用、实施方法及吲哚菁绿标记荧光技术评估吻合口灌注的效果作一综述,旨在为吲哚菁绿标记荧光预防胃癌术后吻合口瘘提供参考。

【Abstract】 Gastric cancer is a malignant tumor originating from the gastric mucosa epithelium. Although the incidence of gastric cancer has declined globally in recent years, it still ranks high. Surgical resection is the main treatment of gastric cancer, which can significantly improve the prognosis of patients, but complications are prone to occur after surgery. Anastomotic leakage is a common and serious complication of gastric cancer patients after surgery, which seriously affects the long-term survival and prognosis of patients. Indocyanine green-labeled fluorescence technology can improve the healing of anastomosis and reduce the incidence of anastomotic fistula by evaluating the anastomotic perfusion during the operation. In this article, the occurrence of anastomotic fistula, introduction of indocyanine green-labeled fluorescence technology, application of indocyanine green-labeled fluorescence technology in gastric cancer surgery, and implementation methods and indocyanine green-labeled fluorescence technology to evaluate the effect of anastomotic perfusion This review aims to provide a reference for indocyanine green labeled fluorescence to prevent anastomotic fistula after gastric cancer surgery.

  • 【文献出处】 医学信息 ,Medical Information , 编辑部邮箱 ,2020年01期
  • 【分类号】R735.2
  • 【被引频次】1
  • 【下载频次】173
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