【摘要】 目的:探讨TomoTherapy Quality Assurance（TQA）数据趋势与螺旋断层放疗（Helical Tomotherapy,HT）系统输出的联系。方法:回顾性分析了本院HT系统近3年内TQA各个模块的参数和数据趋势,探讨其与HT系统的静态输出剂量和输出能量(D₂₀/D₁₀)变化的相关性。结果:楔形阶梯静态模块的z轴偏移参数与HT的静态输出剂量的相关性最强（r=0.883,P<0.01）。基本剂量测定模块的出口检测器平整度值对能量变化最敏感（r=0.902）,其次是楔形阶梯静态模块的能量差异（r=0.897）和楔形阶梯螺旋模块的能量差异（r=0.852）,灵敏度分别为2.3×10^-4、3.1×10^-4和5.7×10^-4。结论:TQA有助于用户追踪HT输出剂量和能量变化,及早进行必要的机器维护或剂量校准。更多还原

【Abstract】 Objective To discuss the relationship between tomotherapy quality assurance（TQA） data trends and output of helical tomotherapy（HT）. Methods The correlations between static output and output energy variation(D₂₀/D₁₀) were determined based on the retrospective analysis on the parameters and data trends of each module of TQA of HT in recent 3 years. Results The offset parameter of z axis in step-wedge static module had the best correlation with the static output of HT（r=0.883, P<0.01）. The exit detector flatness in basic dosimetry module was the most sensitive to energy changes（r=0.902）,followed by energy differences in step-wedge static module（r=0.897） and energy differences in step-wedge helical module（r=0.852）, and their sensitivities were 2.3×10^-4, 3.1×10^-4 and 5.7×10^-4, respectively. Conclusion TQA can help user to monitor the changes in the output and energy of HT, thereby carrying out necessary maintenance and dosimetric validation earlier.更多还原