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基于3D打印的胸部个体化剂量验证体模设计

Design of a 3D printing-based individualized thorax phantom for dose verification

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【作者】 杨元佳童蕾钟安妮陈超敏

【Author】 YANG Yuanjia;TONG Lei;ZHONG Anni;CHEN Chaomin;Department of Medical Instrument, People’s Hospital of Guangning County;Guangdong Mechanical &Electronical Polytechnic;School of Biomedical Engineering, Southern Medical University;

【通讯作者】 陈超敏;

【机构】 广东省广宁县人民医院器械科广东机电职业技术学院南方医科大学生物医学工程学院

【摘要】 目的:为更精确地对治疗计划进行验证,利用3D打印设计出反映患者真实情况的个体化体模。方法:依据病人定位时的CT图像重建并进行3D打印得到患者的三维立体结构空壳,然后以CT值为依据选择各组织的辐射等效材料完成填充,即得到体现病人特征的个体化剂量验证体模。结果:将合成的等效材料行CT扫描,骨组织、肺组织、软组织、肿瘤CT值分别为1 100、-747.6、-22、-471 HU,误差均小于22%。结论:最终设计的胸部体模能够较准确地体现个体之间的差异,等效材料辐射等效性较好,可用于实际剂量验证。

【Abstract】 Objective To design an individual phantom that can reflect the real situation of patients by 3 D printing technology for realizing more accurate treatment plan verification. Methods Based on the reconstruction according to the CT image obtained during positioning, the shell of the three-dimensional structure of the patient was obtained by 3 D printing. Then the shell was filled with radiation tissue-equivalent materials selected according to CT value of each organ, thereby obtaining the individualized phantom which reflected patient’s characteristics and then was used for dose verification. Results The synthetic equivalent materials were scanned with CT. The obtained CT values of bone tissues, lung tissues, soft tissues and tumor were 1 100,-747.6,-22 and-471 HU, respectively, with errors less than 22%. Conclusion The designed thorax phantom can accurately reflect the differences between individuals, and the tissue-equivalent materials have excellent radiation properties. The designed thorax phantom can be used in the actual dose verification.

【基金】 国家重点研发计划(2019YFC0118805)
  • 【文献出处】 中国医学物理学杂志 ,Chinese Journal of Medical Physics , 编辑部邮箱 ,2020年06期
  • 【分类号】R730.55
  • 【被引频次】2
  • 【下载频次】87
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