【摘要】 目的:探讨"五步脱敏疗法"对成瘾患者渴求、线索敏感及成瘾记忆的影响。方法:在湖北省武汉市3所自愿戒毒医院中招募39名甲基苯丙胺依赖患者,随机分配入干预组和对照组。干预组接受连续5天,每天90分钟的"五步脱敏"治疗,在此期间对照组不干预。分别采用"渴求视觉模拟标尺"(VAS)、"线索敏感问卷"(CSQ)和"成瘾记忆强度量表"(AMIS)对患者的渴求、毒品相关线索敏感性及成瘾记忆强度进行测试。结果:研究对象的VAS得分变化存在组别和时间的交互效应(P=0.005),CSQ和AMIS得分变化均存在组别效应(P<0.05)。接受干预后,干预组各测量指标得分均低于对照组。结论:"五步脱敏"治疗可有效降低成瘾患者的渴求水平、对毒品相关线索的敏感程度及其成瘾记忆强度。更多还原

【Abstract】 Objective:To explore the effects of Five-Step Desensitization Therapy(FSDT) on craving, drug-related cue sensitization, and addiction memory among methamphetamine addicts. Methods:A total of 39 methamphetamine addicts were recruited from three hospitals in Wuhan, Hubei Province, and were randomly assigned to be as an intervention group or a control group. Participants in the intervention group received a 5-day(90 min per day) FSDT intervention, while those in the control group waited during this period without intervention. Respectively, the Visual Analogue Scale(VAS), Cue-Sensitization Questionnaire(CSQ), and Addiction Memory Intensity Scale(AMIS) were used to measure the participants′ craving, cue reactivity to drug-related stimuli, and their intensity of addiction memory. Results:Interaction effects of intervention and time were found significantly on the VAS scores(P = 0.005). Intervention effects were found significantly on scores of the CSQ and AMIS(P<0.05). For participants in the intervention group, scores of the VAS, CSQ, and AMIS were significantly less than those in the control group after treatment. Conclusion:The FSDT intervention can decrease the methamphetamine addicts′ craving and reduce their cue reactivity to drug-related stimuli as well as the intensity of addiction memory.更多还原