【摘要】 设计了二苯并噻吩衍生物的合成与表征综合实验。实验主要包括:通过溴化反应、硼酸酯反应、Suzuki偶联反应、格式反应和关环反应合成二苯并噻吩衍生物,并运用核磁共振（NMR）技术(¹H NMR,¹³C NMR, ¹H-¹H COSY,HSQC,HMBC)研究其结构,且报道其波谱峰位的归属。通过该实验,学生可以比较完整、系统地了解有机合成的主要步骤与表征方法,并且通过分析NMR谱图,理解核磁共振技术在有机合成中确定未知物的重要作用。教学实践表明,该综合实验取得了较好的教学效果。更多还原

【Abstract】 This paper aims to design a comprehensive chemical experiment of synthesis and characterization of dibenzothiophene derivatives. The experiment includes synthesis of new dibenzothiophene derivative, and the analysis of chemical structure by NMR(¹H NMR, ¹³C NMR, ¹H-¹H COSY, HSQC, HMBC) techniques, and the NMR signals assignment of the 14,14-dimethyl-14H-benzo[b]benzo[5,6]fluoreno [1,2-d] thiophene. Preparation and characterization of a new compound are one of the compulsory experimental courses for the materials science related field student. Consequently, the students can master the main steps and characterization methods of organic synthesis, and realize the important role of nuclear magnetic resonance technique in determining the structure of new compound. It is proven that the comprehensive experiment has achieved favorite results in practice teaching.更多还原