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血清PG、G-17及Hp对早期胃癌诊断的研究进展
Research progress of serum PG, G-17 and Hp in the diagnosis of early gastric cancer
【摘要】 胃癌是较为常见的恶性肿瘤,但早期症状不明显,诊断困难,多数患者确诊时已为中晚期,失去了治愈的机会。因此,对早期胃癌的诊断至关重要。在我国早期胃癌的诊断主要依靠胃镜及活检,但诊断率低于10%,其主要原因为胃镜作为一种侵入性检查方法,患者接受度差,且检查费用昂贵,难以进行大规模筛查。目前我国为提高早期胃癌患者的诊断率,通过检测胃蛋白酶原(PG)、胃泌素-17(G-17)及幽门螺旋杆菌(Hp)抗体等血清学指标对早期胃癌进行筛查,取得了一定的效果。本文就PG、G-17及Hp对早期胃癌的诊断做一综述。
【Abstract】 Gastric cancer is a common malignant tumor, but the early symptoms are not obvious, and it is difficult to diagnose. Most patients have been diagnosed as middle and late stage and lost the opportunity to cure. Therefore, the diagnosis of early gastric cancer is very important. In China, the diagnosis of early gastric cancer mainly depends on gastroscopy and biopsy, but the diagnosis rate is less than 10%. The main reason is that gastroscopy, as an invasive examination method, has poor patient acceptance and high cost, so it is difficult to carry out large-scale screening. At present, in order to improve the diagnosis rate of patients with early gastric cancer in China, the detection of pepsinogen(PG), gastrin-17(G-17) and Helicobacter pylori(Hp) antibody and other serological indicators for screening of early gastric cancer has achieved certain results. This article reviews the diagnosis of early gastric cancer by PG, G-17 and Hp.
【Key words】 early gastric cancer; pepsinogen; gastrin-17; Helicobacter pylori;
- 【文献出处】 临床医学研究与实践 ,Clinical Research and Practice , 编辑部邮箱 ,2020年34期
- 【分类号】R735.2
- 【被引频次】4
- 【下载频次】333