【摘要】 目的观察长期无创正压通气治疗重度稳定期慢性阻塞性肺疾病(COPD)合并呼吸衰竭患者的临床效果。方法选取我院收治的88例重度稳定期COPD合并呼吸衰竭患者作为研究对象,按照随机数字表法将其分为对照组与观察组,每组44例。对照组给予常规治疗,观察组在对照组基础上加用长期无创正压通气治疗。比较两组治疗效果。结果治疗后,两组患者的PaO2、PaCO2均改善,且观察组优于对照组(P<0.05)。治疗后,观察组急性发作次数及因急性发作住院时间均优于对照组(P<0.05)。结论长期无创正压通气治疗重度稳定期COPD合并呼吸衰竭,对患者血气指标改善作用显著,且能够减少急性发作次数、缩短住院时间,值得推广。更多还原

【Abstract】 Objective To observe the clinical effect of long-term noninvasive positive pressure ventilation on patients with severe stable chronic obstructive pulmonary disease(COPD) complicated with respiratory failure. Methods A total of 88 patients with severe stable COPD complicated with respiratory failure admitted in our hospital were selected as the study objects and divided into control group and observation group according to the random number table method, with 44 cases in each group. The control group was given routine treatment, and the observation group was given long-term noninvasive positive pressure ventilation on the basis of the control group. The therapeutic effects of the two groups were compared.Results After treatment, PaO2 and PaCO2 in both groups improved, and those in the observation group were better than the control group(P <0.05). After treatment, the number of acute attacks and hospitalization time due to acute attacks in the observation group were better than those in the control group(P<0.05). Conclusion Long-term noninvasive positive pressure ventilation in the treatment of severe stable COPD complicated with respiratory failure can significantly improve the blood gas index of patients, reduce the number of acute attacks and shorten hospitalization time, which is worthy of promotion.更多还原