【摘要】 目的分析扩张性心肌病(DCM)心力衰竭患者发生心房颤动(AF)的影响因素。方法回顾性分析我院收治的261例DCM心力衰竭患者的临床资料,根据相关诊断分为AF组(101例)和非AF组(160例),收集并记录两组患者的一般临床资料、血生化、心电图、超声心动图检测结果等,分析DCM心力衰竭患者发生AF的影响因素。结果 AF组患者的平均年龄显著大于非AF组,差异具有统计学意义(P<0.05)。AF组的TG、TC、HDL-C、LDL-C水平及LEVF显著低于非AF组,LAD显著高于非AF组,差异具有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,年龄是DCM心力衰竭患者发生AF的危险因素(OR=1.045,P<0.05);HDL-C、LDL-C及LEVF是DCM心力衰竭患者发生AF的保护因素(OR=0.129、0.465、0.975,P<0.05)。结论高龄、低水平的LDL-C及HDL-C是DCM心力衰竭患者发生AF的独立危险因素,因此在临床治疗DCM心力衰竭时应合理应用降脂药物,适当控制血脂水平,预防AF发生。更多还原

【Abstract】 Objective To analyze the influencing factors of atrial fibrillation(AF) in patients with dilated cardiomyopathy(DCM) and heart failure. Methods The clinical data of 261 DCM patients with heart failure treated in our hospital were analyzed retrospectively. The patients were divided into AF group(101 cases) and non-AF group(160 cases) according to relevant diagnosis. General clinical data, blood biochemistry, electrocardiogram, echocardiogram test results of the two groups of patients were collected and recorded, and the influencing factors of AF in DCM patients with heart failure were analyzed. Results The average age of the AF group was significantly larger than that of the non-AF group, and the difference was statistically significant(P<0.05). The levels of TG, TC, HDL-C, LDL-C and LEVF in the AF group were significantly lower than those of the non-AF group, LAD was significantly higher than that in the non-AF group, and the differences were statistically significant(P<0.05). Multivariate Logistic regression analysis showed that age was risk factor for AF in DCM patients with heart failure(OR=1.045, P<0.05); HDL-C, LDL-C and LVEF were protective factors for AF in DCM patients with heart failure(OR=0.129, 0.465, 0.975, P<0.05). Conclusion Old age, low levels of LDL-C and HDL-C are independent risk factors for AF in DCM patients with heart failure. So in the clinical treatment of DCM and heart failure, we should reasonably use lipid-lowering drugs and properly control the levels of blood lipids to prevent the incidence of AF.更多还原