【摘要】 玻璃体腔注射抗血管内皮生成因子(anti-vascular endothelia growth factor,VEGF)是目前湿性年龄相关性黄斑变性(wet age-related macular degeneration,wAMD)的标准治疗方案,但其治疗应答却存在个体差异。本文总结概括了遗传因素、基线视力、治疗时机、光学相干断层扫描成像(optical coherence tomography,OCT)及光学相干断层扫描血管成像(optical coherence tomography angiography,OCTA)上的影像学特征等对抗VEGF治疗应答有影响的临床基线特征,以期为选择治疗方案及预测预后提供依据。更多还原

【Abstract】 Current standard treatment of wet age-related macular degeneration (wAMD) is an intravitreal anti-vascular endothelia growth factor (anti-VEGF) therapy,but responses to treatment show large variability.This review summarizes genetic factors,baseline vision,treatment time,morphological characteristics shown on OCT and OCTA and other clinical baseline characteristics,which were associated with the response to the therapy,aiming to help select treatment regimen and predict the response to anti-VEGF therapy.更多还原