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米索前列醇、宫颈扩张球囊和缩宫素在妊娠晚期引产中的应用研究

Application of misoprostol,cervical dilatation balloon and oxytocin in induction of labor in late pregnancy

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【作者】 崔张霞张梅薛翔

【Author】 CUI Zhang-xia;ZHANG Mei;XUE Xiang;Xi′an Jiao Tong University Health Science Center;The Second Clinical Hospital Affiliated to Shaanxi University of Traditional Chinese Medicine;Wuqi County People′s Hospital;

【通讯作者】 薛翔;

【机构】 西安交通大学第二附属医院陕西中医药大学第二附属医院吴起县人民医院

【摘要】 目的探究米索前列醇、宫颈扩张球囊和缩宫素在妊娠晚期引产中的应用效果。方法选取妊娠晚期单胎、头位、初产妇240例,随机分成3组,每组80例。A、B组作为实验组,C组作为对照组,A组给予米索前列醇片阴道后穹窿放药,B组给予一次性宫颈扩张球囊,C组给予缩宫素静脉滴注,观察并比较3组促宫颈成熟有效率、妊娠结局及分娩并发症。结果 A、B组促宫颈成熟有效率及引产成功率明显高于C组(P<0.05),A、B两组比较差别无显著性(P>0.05);干预至分娩时间C组明显长于A、B组(P<0.05),B组长于A组(P<0.05)。三组阴道分娩率、分娩并发症无显著差异(P>0.05)。结论对妊娠晚期宫颈不成熟的引产,米索前列醇组和宫颈扩张球囊组能够明显提高引产成功率,缩短临产时间,效果优于缩宫素组。

【Abstract】 Objective To explore the application effect of misoprostol,cervical dilatation balloon and oxytocin in induction of labor in late pregnancy.Methods 240 cases of singleton,head position and primipara were randomly divided into three groups,80 cases in each group.Group A and B was used as the experimental group,group C as the control group,group A was given misoprostol tablets for vaginal posterior fornix,group B was given one-time cervical dilatation balloon,group C was given oxytocin intravenous drip,observe and compare the efficiency of cervical ripening,pregnancy outcome and delivery complications of the three groups.Results The effective rate of cervical ripening and the successful rate of induced labor in group A and B were significantly higher than those in group C(P< 0.05),but there was no significant difference between group A and B(P> 0.05);the time from intervention to delivery in group C was significantly longer than that in group A and B(P< 0.05),and group B was longer than that in group A(P< 0.05).There was no significant difference in vaginal delivery rate and delivery complications among the three groups(P> 0.05).Conclusion Misoprostol group and cervical dilation balloon group can significantly improve the success rate of induction of labor and shorten the time of labor,the effect is better than oxytocin group.

  • 【文献出处】 延安大学学报(医学科学版) ,Journal of Yanan University(Medical Science Edition) , 编辑部邮箱 ,2020年03期
  • 【分类号】R719.3
  • 【被引频次】3
  • 【下载频次】103
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