【摘要】 高血压作为心血管疾病及死亡的一种常见危险因素,严重威胁着人类健康。抗高血压药物治疗可有效降压,减少靶器官损害,有效预防心血管疾病事件。临床常用的降压药物包括钙通道阻滞剂、血管紧张素转化酶抑制剂、血管紧张素Ⅱ受体阻滞剂、利尿剂、β受体阻滞剂及α受体阻滞剂等。近年随着药物研发进展,产生一些新型降压药物。现综述新型降压药物进展,以期为临床降压治疗提供新参考。更多还原

【Abstract】 Hypertension is a leading risk factor for cardiovascular diseases and death,and being a threat for human health. Antihypertensive drugs including calcium channel blocker,angiotensin converting enzyme inhibitors,angiotensin receptor blockers,diuretics,betaadrenoceptors and alpha-adrenoceptors,are common used at present,which are effectively to control the high blood plessure,reduce target organ damage,and prevent the cardiovascular events. With the developing of drug research,novel anti-hypertensive drugs were produced. This paper summarizes the current advance of novel anti-hypertensive drugs,which may offer the help for clinical practice.更多还原