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心力衰竭合并贫血和铁缺乏的诊治进展
Diagnosis and Treatment of Anemia and Iron Deficiency in Heart Failure
【摘要】 心力衰竭(心衰)是所有心脏疾病的严重表现或晚期阶段,目前心衰的发病机制和治疗的研究已有显著进展,预后得到改善,但仍不容乐观。贫血和铁缺乏是心衰常见的合并症,无论共存或独立,都与心衰预后不良有关。积极纠正贫血和铁缺乏有助于改善心衰患者症状和提高生活质量。红细胞生成刺激剂常用于心衰患者贫血的纠正,但并未改善预后,且增加不良事件风险。口服补铁方便易得,静脉补铁能改善心衰症状和运动能力,但两者的长期疗效和安全性需进一步研究。
【Abstract】 Heart failure is the severe manifestation or advanced stage of all heart diseases.At present,the pathogenesis and treatment of heart failure have already made significant progress,and the prognosis has improved,but it is still not optimistic.Anemia and iron deficiency are common combinations of heart failure.Both conditions,together or independently,are associated with poor prognosis for heart failure.Actively correcting anemia and iron deficiency can help improve symptoms and quality of life in patients with heart failure.Erythropoiesis-stimulating agents are commonly used to correct anemia in patients with heart failure,but they do not improve prognosis and increase the risk of adverse events.Oral iron supplementation is convenient and readily available,and intravenous iron supplementation can improve symptoms and exercise capacity,but the long-term efficacy and safety of both need further study.
- 【文献出处】 心血管病学进展 ,Advances in Cardiovascular Diseases , 编辑部邮箱 ,2020年05期
- 【分类号】R541.6;R556
- 【被引频次】4
- 【下载频次】280